Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 419267..419940 Replicon chromosome
Accession NZ_CP036402
Organism Egibacter rhizosphaerae strain EGI 80759

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ER308_RS01930 Protein ID WP_131153445.1
Coordinates 419512..419940 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ER308_RS01925 Protein ID WP_131153444.1
Coordinates 419267..419515 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ER308_RS01900 414554..415653 + 1100 Protein_373 ISL3 family transposase -
ER308_RS01905 415997..417079 - 1083 WP_131153440.1 IS630 family transposase -
ER308_RS01910 417308..417688 - 381 WP_131153441.1 metalloregulator ArsR/SmtB family transcription factor -
ER308_RS01915 417685..418320 - 636 WP_131153442.1 SRPBCC family protein -
ER308_RS01920 418525..419244 + 720 WP_131153443.1 DNA alkylation repair protein -
ER308_RS01925 419267..419515 + 249 WP_131153444.1 antitoxin Antitoxin
ER308_RS01930 419512..419940 + 429 WP_131153445.1 type II toxin-antitoxin system VapC family toxin Toxin
ER308_RS01935 420025..421077 - 1053 WP_205745841.1 ABC transporter substrate-binding protein -
ER308_RS01940 421121..422056 - 936 WP_131153446.1 ABC transporter ATP-binding protein -
ER308_RS01945 422071..423159 - 1089 WP_131153447.1 iron ABC transporter permease -
ER308_RS01950 423171..424148 - 978 WP_205745842.1 iron chelate uptake ABC transporter family permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 415489..415653 164


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-138)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15702.99 Da        Isoelectric Point: 6.7611

>T119741 WP_131153445.1 NZ_CP036402:419512-419940 [Egibacter rhizosphaerae]
VKLVDANVLLYAVNVDAERHKPSRRWLDRALSGQDTVAFAWVVLLAFVRLATRDGLFPSPLTIDDAMDRVDGWLAAPPAV
VVHPTLEHARLVRDLLRGLGAGGNLVNDAHLAALAIEHRGTIVSFDHDFDRFEGVRREAPRI

Download         Length: 429 bp

>T119741 NZ_CP036402:419512-419940 [Egibacter rhizosphaerae]
GTGAAGCTCGTCGACGCGAACGTCCTGCTGTACGCGGTCAACGTGGACGCCGAGCGCCACAAGCCGTCACGACGATGGCT
CGACCGAGCCTTGTCCGGGCAGGACACGGTCGCGTTCGCGTGGGTCGTCCTGCTCGCGTTCGTGCGCCTTGCCACCCGCG
ACGGGCTGTTCCCCTCGCCGTTGACGATCGACGACGCGATGGACCGTGTCGACGGGTGGCTGGCCGCCCCACCGGCCGTC
GTGGTGCACCCCACCCTCGAGCACGCGCGACTCGTGCGGGACCTCCTTCGCGGGCTGGGAGCAGGCGGCAACCTCGTCAA
CGACGCGCACCTCGCGGCGCTGGCGATCGAGCACCGCGGCACGATCGTGTCCTTCGACCACGACTTCGACCGCTTCGAGG
GCGTGCGCCGAGAGGCACCCCGGATCTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.15 Da        Isoelectric Point: 4.8283

>AT119741 WP_131153444.1 NZ_CP036402:419267-419515 [Egibacter rhizosphaerae]
MRTTVTLDPDTAQIVRRRMRERGMTFKEALNDVIRSGAGDTAEEFQTPTASLGRPSVNLDRALQVAGDLEDEDLVRKERA
GS

Download         Length: 249 bp

>AT119741 NZ_CP036402:419267-419515 [Egibacter rhizosphaerae]
ATGCGGACGACCGTGACCCTGGACCCCGACACCGCGCAGATCGTGCGGCGTCGGATGCGCGAGCGCGGGATGACGTTCAA
GGAAGCGCTCAACGACGTCATCCGCAGCGGCGCGGGGGATACTGCCGAGGAGTTCCAGACACCGACCGCCTCGCTCGGAC
GCCCGTCGGTGAACCTCGACCGCGCGCTGCAGGTCGCCGGTGACCTCGAGGACGAGGACCTTGTTCGCAAGGAGCGGGCC
GGCTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References