Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4252409..4252554 Replicon chromosome
Accession NZ_CP036365
Organism Klebsiella pneumoniae strain WCHKP115068

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4252416..4252518 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4252409..4252554 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DVJ72_RS21495 4247941..4249374 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
DVJ72_RS21500 4249490..4249729 + 240 WP_002911393.1 YebV family protein -
DVJ72_RS21505 4249827..4250018 + 192 WP_002911395.1 YebW family protein -
DVJ72_RS21510 4250015..4250668 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
DVJ72_RS21515 4250825..4251793 + 969 WP_004151446.1 VirK/YbjX family protein -
DVJ72_RS29850 4251898..4252041 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4252409..4252554 + 146 - - Antitoxin
- 4252416..4252518 - 103 - - Toxin
DVJ72_RS21525 4252677..4253015 - 339 WP_002911404.1 YebY family protein -
DVJ72_RS21530 4253032..4253901 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
DVJ72_RS21535 4253905..4254279 - 375 WP_004151448.1 CopC domain-containing protein YobA -
DVJ72_RS21540 4254392..4254622 + 231 WP_002911406.1 DNA polymerase III subunit theta -
DVJ72_RS21545 4254701..4255360 + 660 WP_002911407.1 exodeoxyribonuclease X -
DVJ72_RS21550 4255364..4257424 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T119649 NZ_CP036365:c4252518-4252416 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT119649 NZ_CP036365:4252409-4252554 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References