Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2041549..2041694 Replicon chromosome
Accession NZ_CP036361
Organism Klebsiella pneumoniae strain WCHKP2080

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2041585..2041687 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2041549..2041694 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7D45_RS10245 2036679..2038739 + 2061 WP_004151449.1 oligopeptidase B -
B7D45_RS10250 2038743..2039402 - 660 WP_002911407.1 exodeoxyribonuclease X -
B7D45_RS10255 2039481..2039711 - 231 WP_002911406.1 DNA polymerase III subunit theta -
B7D45_RS10260 2039824..2040198 + 375 WP_004151448.1 CopC domain-containing protein YobA -
B7D45_RS10265 2040202..2041071 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
B7D45_RS10270 2041088..2041426 + 339 WP_002911404.1 YebY family protein -
- 2041549..2041694 - 146 - - Antitoxin
- 2041585..2041687 + 103 - - Toxin
B7D45_RS28990 2042062..2042205 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
B7D45_RS10280 2042310..2043278 - 969 WP_004151446.1 VirK/YbjX family protein -
B7D45_RS10285 2043435..2044088 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
B7D45_RS10290 2044085..2044276 - 192 WP_002911395.1 YebW family protein -
B7D45_RS10295 2044374..2044613 - 240 WP_002911393.1 YebV family protein -
B7D45_RS10300 2044729..2046162 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T119621 NZ_CP036361:2041585-2041687 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT119621 NZ_CP036361:c2041694-2041549 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References