Detailed information of TA system TA119611

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /SpoIISA(toxin)
• Location: 4497333..4498296
• Replicon: chromosome
• Accession: NZ_CP036356
• Organism: Bacillus sp. SYJ

Toxin (Protein)

• Gene name: spoIISA
• Uniprot ID: -
• Locus tag: EYB51_RS24575
• Protein ID: WP_131102745.1
• Coordinates: 4497333..4498070 (+)
• Length: 246 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: EYB51_RS24580
• Protein ID: WP_029438356.1
• Coordinates: 4498168..4498296 (+)
• Length: 43 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EYB51_RS24550	4492369..4492776	+	408	WP_078985373.1	VOC family protein	-
EYB51_RS24555	4493064..4493846	+	783	WP_087963875.1	class I SAM-dependent methyltransferase	-
EYB51_RS24560	4493968..4495653	-	1686	WP_131102165.1	alpha-keto acid decarboxylase family protein	-
EYB51_RS24565	4495760..4496242	+	483	WP_087963877.1	MarR family winged helix-turn-helix transcriptional regulator	-
EYB51_RS24570	4496409..4497146	+	738	WP_087963878.1	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	-
EYB51_RS24575	4497333..4498070	+	738	WP_131102745.1	type II toxin-antitoxin system SpoIISA family toxin	Toxin
EYB51_RS24580	4498168..4498296	+	129	WP_029438356.1	hypothetical protein	Antitoxin
EYB51_RS29040	4498369..4498545	+	177	WP_087963880.1	hypothetical protein	-
EYB51_RS24585	4498753..4500222	+	1470	WP_087963881.1	beta-Ala-His dipeptidase	-
EYB51_RS24590	4500734..4501204	-	471	WP_087963883.1	DUF5065 family protein	-
EYB51_RS24595	4501660..4502319	+	660	WP_131102167.1	CatB-related O-acetyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SpoIISA, type II toxin-antitoxin system (9-243)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 246 a.a.
• Molecular weight: 28415.26 Da
• Isoelectric Point: 8.2638

>T119611 WP_131102745.1 NZ_CP036356:4497333-4498070 [Bacillus sp. SYJ]
VISNIRIGLFILAIVFLLLIFFYWKNEELYEEKKQRIRKTWYGLFIISVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYTKSLNAFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSIMIPLEYIEQLNEQKAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFIK

Nucleotide

• Length: 738 bp

>T119611 NZ_CP036356:4497333-4498070 [Bacillus sp. SYJ]
GTGATCTCTAACATTCGAATCGGCTTATTTATTTTAGCAATCGTTTTTCTATTACTTATTTTCTTCTATTGGAAAAACGA
AGAGTTGTACGAGGAGAAGAAGCAACGTATTCGAAAGACTTGGTATGGGTTGTTTATAATATCAGTCACCGTATATTTCA
TGATAAAAGGAATTGATTTAACCCTCTGGAAAAATCTTTTAATGTTCACTGCAATGGTTATTTTCGTTGATATTGCATTT
ATTTTAACACCTAATATTTCAGAAATATGGGGAGCGAAATTTAGCGATATCGGCAAGACGGTTCAATCGATAAAACGGTC
ATTAATTGCTTCTAAAGCAAGAGGAGAAATATACACAACAATTATTCAAAATGTCAATCCAGCAGTATTCGGTACGATGG
AATGGCATACGGAGGAAGAATATACAAAAAGCTTAAACGCATTTTTAGATTCGTACGGGGAAAAGATTGGAGCAAAAATT
GTTGTATTTGAAGCGGCAAAGGAATTGAATACAAACTTTCGTGGTATCCGTTCTCAATTCAGTATTATGATTCCGTTAGA
GTATATTGAGCAATTGAATGAGCAGAAAGCAGTGCAAGTAGAAAATGTCGGAATTATACCAGCAAAAATAGTGAGTGATG
TTTTCATTGTTATTGACGGGAAGAAAAATAATCTTCAAGACCGGGATTTTGAAAATGTATATAATTTAACGATACATCAT
AGTTATTTTATTAAGTAG

Antitoxin

Protein

• Length: 43 a.a.
• Molecular weight: 5025.42 Da
• Isoelectric Point: 3.9150

>AT119611 WP_029438356.1 NZ_CP036356:4498168-4498296 [Bacillus sp. SYJ]
VIKDYDNDFFKEDNEDTTDFSLIKGDTLQQVEELEEELKRKS

Nucleotide

• Length: 129 bp

>AT119611 NZ_CP036356:4498168-4498296 [Bacillus sp. SYJ]
GTGATAAAAGATTATGACAATGATTTTTTCAAAGAAGATAATGAAGATACAACTGATTTCTCTTTAATAAAAGGAGATAC
GTTGCAGCAAGTAGAAGAGTTAGAAGAAGAATTAAAAAGAAAATCATAA