Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 46642..46787 Replicon chromosome
Accession NZ_CP036327
Organism Klebsiella pneumoniae strain BA28434

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 46678..46780 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 46642..46787 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3E96_RS00235 41772..43832 + 2061 WP_004151449.1 oligopeptidase B -
C3E96_RS00240 43836..44495 - 660 WP_002911407.1 exodeoxyribonuclease X -
C3E96_RS00245 44574..44804 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C3E96_RS00250 44917..45291 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C3E96_RS00255 45295..46164 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
C3E96_RS00260 46181..46519 + 339 WP_002911404.1 YebY family protein -
- 46642..46787 - 146 - - Antitoxin
- 46678..46780 + 103 - - Toxin
C3E96_RS29010 47156..47299 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C3E96_RS00270 47404..48372 - 969 WP_004151446.1 VirK/YbjX family protein -
C3E96_RS00275 48529..49182 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
C3E96_RS00280 49179..49370 - 192 WP_002911395.1 YebW family protein -
C3E96_RS00285 49468..49707 - 240 WP_002911393.1 YebV family protein -
C3E96_RS00290 49823..51256 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3783..54013 50230


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T119567 NZ_CP036327:46678-46780 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT119567 NZ_CP036327:c46787-46642 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References