Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2019504..2019649 | Replicon | chromosome |
| Accession | NZ_CP036300 | ||
| Organism | Klebsiella pneumoniae subsp. pneumoniae strain WCHKP015093 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2019540..2019642 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2019504..2019649 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CLQ99_RS10130 | 2014634..2016694 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| CLQ99_RS10135 | 2016698..2017357 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| CLQ99_RS10140 | 2017436..2017666 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| CLQ99_RS10145 | 2017779..2018153 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| CLQ99_RS10150 | 2018157..2019026 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| CLQ99_RS10155 | 2019043..2019381 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2019504..2019649 | - | 146 | - | - | Antitoxin |
| - | 2019540..2019642 | + | 103 | - | - | Toxin |
| CLQ99_RS30350 | 2020017..2020160 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| CLQ99_RS10165 | 2020265..2021233 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| CLQ99_RS10170 | 2021390..2022043 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| CLQ99_RS10175 | 2022040..2022231 | - | 192 | WP_002911395.1 | YebW family protein | - |
| CLQ99_RS10180 | 2022329..2022568 | - | 240 | WP_002911393.1 | YebV family protein | - |
| CLQ99_RS10185 | 2022684..2024117 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T119481 NZ_CP036300:2019540-2019642 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT119481 NZ_CP036300:c2019649-2019504 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT