Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2019504..2019649 Replicon chromosome
Accession NZ_CP036300
Organism Klebsiella pneumoniae subsp. pneumoniae strain WCHKP015093

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2019540..2019642 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2019504..2019649 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLQ99_RS10130 2014634..2016694 + 2061 WP_004151449.1 oligopeptidase B -
CLQ99_RS10135 2016698..2017357 - 660 WP_002911407.1 exodeoxyribonuclease X -
CLQ99_RS10140 2017436..2017666 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CLQ99_RS10145 2017779..2018153 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CLQ99_RS10150 2018157..2019026 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
CLQ99_RS10155 2019043..2019381 + 339 WP_002911404.1 YebY family protein -
- 2019504..2019649 - 146 - - Antitoxin
- 2019540..2019642 + 103 - - Toxin
CLQ99_RS30350 2020017..2020160 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CLQ99_RS10165 2020265..2021233 - 969 WP_004151446.1 VirK/YbjX family protein -
CLQ99_RS10170 2021390..2022043 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CLQ99_RS10175 2022040..2022231 - 192 WP_002911395.1 YebW family protein -
CLQ99_RS10180 2022329..2022568 - 240 WP_002911393.1 YebV family protein -
CLQ99_RS10185 2022684..2024117 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T119481 NZ_CP036300:2019540-2019642 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT119481 NZ_CP036300:c2019649-2019504 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References