Detailed information of TA system TA119477

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yoeB-relB/YoeB-YefM
• Location: 4491763..4492265
• Replicon: chromosome
• Accession: NZ_CP036299
• Organism: Planctopirus ephydatiae strain spb1

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: Spb1_RS16710
• Protein ID: WP_145302749.1
• Coordinates: 4491763..4492017 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: Spb1_RS16715
• Protein ID: WP_145302752.1
• Coordinates: 4492014..4492265 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Spb1_RS16685	4487186..4487485	+	300	Protein_3286	hypothetical protein	-
Spb1_RS16690	4487706..4488131	-	426	WP_145302739.1	hypothetical protein	-
Spb1_RS16695	4488280..4489203	-	924	WP_145304651.1	DUF1559 domain-containing protein	-
Spb1_RS16700	4489721..4490680	+	960	WP_145302742.1	DUF1559 domain-containing protein	-
Spb1_RS16705	4490787..4491191	+	405	WP_145302745.1	hypothetical protein	-
Spb1_RS16710	4491763..4492017	-	255	WP_145302749.1	Txe/YoeB family addiction module toxin	Toxin
Spb1_RS16715	4492014..4492265	-	252	WP_145302752.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
Spb1_RS16720	4492571..4492831	+	261	WP_145302756.1	hypothetical protein	-
Spb1_RS16725	4492918..4494363	-	1446	WP_145302759.1	DUF1501 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (2-72)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10181.81 Da
• Isoelectric Point: 9.7614

>T119477 WP_145302749.1 NZ_CP036299:c4492017-4491763 [Planctopirus ephydatiae]
MKLIFAEAAWEDYLYWQQHDRRMVERINKLVKEIVREPFTGIGKPEPLKHALAGFWSRRITDEHRIVYRIDGNALLIAQL
RYHY

Nucleotide

• Length: 255 bp

>T119477 NZ_CP036299:c4492017-4491763 [Planctopirus ephydatiae]
ATGAAGTTGATCTTCGCCGAAGCCGCCTGGGAAGATTATCTGTACTGGCAGCAACATGACCGGCGGATGGTTGAACGGAT
CAACAAGCTGGTGAAAGAAATTGTGCGTGAGCCATTTACCGGAATTGGTAAACCAGAGCCTCTGAAGCATGCGCTGGCTG
GATTCTGGTCGCGGAGGATCACCGATGAACACCGCATCGTCTACAGAATCGATGGTAACGCCTTGCTGATTGCTCAGTTA
CGCTATCATTATTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9140.39 Da
• Isoelectric Point: 5.0361

>AT119477 WP_145302752.1 NZ_CP036299:c4492265-4492014 [Planctopirus ephydatiae]
VDAISYSTARANLANTMNRVCEDHEPLIITRNGQQSVVMLSLEDFTALEETAYLLRNPANAKRLLAAMEQLGAGHGVERK
LVE

Nucleotide

• Length: 252 bp

>AT119477 NZ_CP036299:c4492265-4492014 [Planctopirus ephydatiae]
GTGGATGCCATTTCGTACTCGACTGCGCGTGCTAATCTGGCGAATACGATGAATCGTGTTTGCGAAGACCACGAACCGCT
GATTATCACCCGCAATGGGCAGCAGTCGGTCGTCATGCTTTCGCTTGAAGATTTTACAGCACTGGAAGAGACGGCTTACC
TGTTGCGGAATCCGGCGAATGCCAAACGCCTGCTCGCTGCCATGGAGCAACTTGGTGCCGGTCATGGGGTCGAGCGAAAG
CTTGTGGAATGA