Detailed information of TA system TA119469

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 1402592..1403114
• Replicon: chromosome
• Accession: NZ_CP036282
• Organism: Rhodoferax sediminis strain Gr-4

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: EXZ61_RS06570
• Protein ID: WP_142810214.1
• Coordinates: 1402592..1402855 (+)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: EXZ61_RS06575
• Protein ID: WP_142810216.1
• Coordinates: 1402845..1403114 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EXZ61_RS06550	1398535..1398729	+	195	WP_142810210.1	hypothetical protein	-
EXZ61_RS06555	1398719..1399621	-	903	WP_142814137.1	alpha/beta hydrolase	-
EXZ61_RS06560	1399647..1401455	+	1809	WP_142810212.1	AMP-binding protein	-
EXZ61_RS06565	1401475..1402248	+	774	WP_142814138.1	hypothetical protein	-
EXZ61_RS06570	1402592..1402855	+	264	WP_142810214.1	BrnT family toxin	Toxin
EXZ61_RS06575	1402845..1403114	+	270	WP_142810216.1	CopG family transcriptional regulator	Antitoxin
EXZ61_RS06580	1403132..1403602	+	471	WP_142810218.1	GIY-YIG nuclease family protein	-
EXZ61_RS06585	1404000..1405064	+	1065	WP_142810220.1	aldo/keto reductase	-
EXZ61_RS06590	1405081..1405713	-	633	WP_142810222.1	hypothetical protein	-
EXZ61_RS06595	1405772..1406260	+	489	WP_142810224.1	aminoacyl-tRNA deacylase	-
EXZ61_RS06600	1406345..1407007	+	663	WP_178084878.1	glycerol-3-phosphate 1-O-acyltransferase PlsY	-
EXZ61_RS06605	1407004..1407963	-	960	WP_142810226.1	phosphodiesterase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (6-81)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 9910.17 Da
• Isoelectric Point: 5.1133

>T119469 WP_142810214.1 NZ_CP036282:1402592-1402855 [Rhodoferax sediminis]
MNSFEFDTAKSESNRAKHGIDFVEAQGLWNDPMLLEIPAKTDDEPRYLVIGLIDGKHWSAVITYRGANVRLISVRRARTE
EVALYES

Nucleotide

• Length: 264 bp

>T119469 NZ_CP036282:1402592-1402855 [Rhodoferax sediminis]
ATGAACTCCTTCGAATTTGACACCGCAAAGAGCGAATCTAATCGCGCGAAACACGGTATCGATTTCGTCGAAGCGCAAGG
TCTCTGGAATGACCCGATGCTGCTGGAAATCCCGGCAAAAACGGATGATGAGCCGCGGTATCTGGTGATAGGGCTAATTG
ATGGGAAGCATTGGTCGGCCGTCATTACCTACCGCGGGGCCAATGTCCGATTGATATCCGTGCGACGTGCACGCACAGAA
GAGGTGGCACTTTATGAAAGCTAA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10259.76 Da
• Isoelectric Point: 10.3084

>AT119469 WP_142810216.1 NZ_CP036282:1402845-1403114 [Rhodoferax sediminis]
MKAKKFEQQFDEDVDVMASLDLSKAKRVLQEQKRVNVDFPTWMIDSLDREANKLGVTRQSVIKVWLAERLEATASNLPFQ
RTRAGAAHR

Nucleotide

• Length: 270 bp

>AT119469 NZ_CP036282:1402845-1403114 [Rhodoferax sediminis]
ATGAAAGCTAAAAAGTTCGAGCAACAGTTTGATGAGGACGTCGACGTTATGGCTTCTTTGGACTTGTCCAAGGCCAAACG
CGTGCTGCAAGAGCAGAAGCGAGTGAATGTCGATTTTCCAACATGGATGATTGACTCGCTAGACCGCGAAGCTAACAAAC
TAGGGGTTACACGGCAGTCTGTTATCAAAGTCTGGCTGGCCGAGCGCCTTGAGGCGACCGCTTCTAACTTGCCGTTCCAA
CGGACGCGCGCAGGTGCGGCGCACCGCTGA