Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1402592..1403114 Replicon chromosome
Accession NZ_CP036282
Organism Rhodoferax sediminis strain Gr-4

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag EXZ61_RS06570 Protein ID WP_142810214.1
Coordinates 1402592..1402855 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag EXZ61_RS06575 Protein ID WP_142810216.1
Coordinates 1402845..1403114 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EXZ61_RS06550 1398535..1398729 + 195 WP_142810210.1 hypothetical protein -
EXZ61_RS06555 1398719..1399621 - 903 WP_142814137.1 alpha/beta hydrolase -
EXZ61_RS06560 1399647..1401455 + 1809 WP_142810212.1 AMP-binding protein -
EXZ61_RS06565 1401475..1402248 + 774 WP_142814138.1 hypothetical protein -
EXZ61_RS06570 1402592..1402855 + 264 WP_142810214.1 BrnT family toxin Toxin
EXZ61_RS06575 1402845..1403114 + 270 WP_142810216.1 CopG family transcriptional regulator Antitoxin
EXZ61_RS06580 1403132..1403602 + 471 WP_142810218.1 GIY-YIG nuclease family protein -
EXZ61_RS06585 1404000..1405064 + 1065 WP_142810220.1 aldo/keto reductase -
EXZ61_RS06590 1405081..1405713 - 633 WP_142810222.1 hypothetical protein -
EXZ61_RS06595 1405772..1406260 + 489 WP_142810224.1 aminoacyl-tRNA deacylase -
EXZ61_RS06600 1406345..1407007 + 663 WP_178084878.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
EXZ61_RS06605 1407004..1407963 - 960 WP_142810226.1 phosphodiesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 9910.17 Da        Isoelectric Point: 5.1133

>T119469 WP_142810214.1 NZ_CP036282:1402592-1402855 [Rhodoferax sediminis]
MNSFEFDTAKSESNRAKHGIDFVEAQGLWNDPMLLEIPAKTDDEPRYLVIGLIDGKHWSAVITYRGANVRLISVRRARTE
EVALYES

Download         Length: 264 bp

>T119469 NZ_CP036282:1402592-1402855 [Rhodoferax sediminis]
ATGAACTCCTTCGAATTTGACACCGCAAAGAGCGAATCTAATCGCGCGAAACACGGTATCGATTTCGTCGAAGCGCAAGG
TCTCTGGAATGACCCGATGCTGCTGGAAATCCCGGCAAAAACGGATGATGAGCCGCGGTATCTGGTGATAGGGCTAATTG
ATGGGAAGCATTGGTCGGCCGTCATTACCTACCGCGGGGCCAATGTCCGATTGATATCCGTGCGACGTGCACGCACAGAA
GAGGTGGCACTTTATGAAAGCTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10259.76 Da        Isoelectric Point: 10.3084

>AT119469 WP_142810216.1 NZ_CP036282:1402845-1403114 [Rhodoferax sediminis]
MKAKKFEQQFDEDVDVMASLDLSKAKRVLQEQKRVNVDFPTWMIDSLDREANKLGVTRQSVIKVWLAERLEATASNLPFQ
RTRAGAAHR

Download         Length: 270 bp

>AT119469 NZ_CP036282:1402845-1403114 [Rhodoferax sediminis]
ATGAAAGCTAAAAAGTTCGAGCAACAGTTTGATGAGGACGTCGACGTTATGGCTTCTTTGGACTTGTCCAAGGCCAAACG
CGTGCTGCAAGAGCAGAAGCGAGTGAATGTCGATTTTCCAACATGGATGATTGACTCGCTAGACCGCGAAGCTAACAAAC
TAGGGGTTACACGGCAGTCTGTTATCAAAGTCTGGCTGGCCGAGCGCCTTGAGGCGACCGCTTCTAACTTGCCGTTCCAA
CGGACGCGCGCAGGTGCGGCGCACCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References