Detailed information of TA system TA119462

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 290688..291339
• Replicon: chromosome
• Accession: NZ_CP036274
• Organism: Anatilimnocola aggregata strain ETA_A8

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: ETAA8_RS00970
• Protein ID: WP_202921485.1
• Coordinates: 290941..291339 (+)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: ETAA8_RS00965
• Protein ID: WP_145083563.1
• Coordinates: 290688..290921 (+)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ETAA8_RS00960	287879..290539	+	2661	WP_145083560.1	ATP-dependent chaperone ClpB	-
ETAA8_RS00965	290688..290921	+	234	WP_145083563.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
ETAA8_RS00970	290941..291339	+	399	WP_202921485.1	type II toxin-antitoxin system VapC family toxin	Toxin
ETAA8_RS00975	291369..293198	-	1830	WP_145083568.1	S8 family serine peptidase	-
ETAA8_RS00980	293309..293752	-	444	WP_145083571.1	flagellar assembly protein FliW	-
ETAA8_RS00985	294376..294669	+	294	WP_145083574.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (1-119)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 14456.86 Da
• Isoelectric Point: 6.6955

>T119462 WP_202921485.1 NZ_CP036274:290941-291339 [Anatilimnocola aggregata]
MLDTNTCIAAMRNHPLVARRLLALNPGDCGISTITAYELFTGVEKCADPTQERRKVELFLQMVSLLPFDSIAAVEAARIR
AALEKLGHTIGPYDLLLAGHALSLRLILATNNTGEFLRVRGLTVEDWQCPAP

Nucleotide

• Length: 399 bp

>T119462 NZ_CP036274:290941-291339 [Anatilimnocola aggregata]
TTGCTCGACACCAATACGTGCATTGCGGCCATGCGGAATCATCCGCTGGTGGCGAGACGATTGCTGGCCCTGAACCCTGG
CGACTGCGGGATATCGACCATCACTGCATATGAGTTATTCACTGGCGTCGAAAAGTGTGCGGATCCAACACAAGAGCGTC
GTAAGGTAGAGCTATTTTTGCAGATGGTGAGCTTACTCCCATTTGACTCAATTGCGGCGGTAGAGGCAGCCCGAATCCGA
GCAGCGCTTGAGAAGCTTGGACATACCATTGGACCTTACGATCTGTTGCTCGCAGGACACGCCTTGTCGTTGCGACTTAT
CCTGGCCACTAACAACACCGGGGAGTTTTTACGAGTCAGAGGATTGACTGTGGAAGATTGGCAATGCCCGGCACCTTAG

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8474.67 Da
• Isoelectric Point: 4.4963

>AT119462 WP_145083563.1 NZ_CP036274:290688-290921 [Anatilimnocola aggregata]
MKTAEVIELQGMQAVKLPEEFRFDGSSVSIRRAGEAVILEPMKPATWPANFLESIHVDDPAFVRPEQGQTPPAPNLS

Nucleotide

• Length: 234 bp

>AT119462 NZ_CP036274:290688-290921 [Anatilimnocola aggregata]
ATGAAGACCGCTGAAGTGATCGAGTTACAGGGGATGCAGGCCGTCAAGTTGCCCGAGGAATTTCGTTTTGACGGATCGAG
CGTATCGATTCGCAGGGCGGGAGAAGCGGTAATTCTCGAGCCGATGAAGCCTGCAACTTGGCCTGCCAATTTTTTGGAAT
CCATTCATGTTGACGATCCGGCATTCGTCCGTCCTGAGCAAGGACAGACACCACCAGCCCCCAACTTGAGTTGA