Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 142335..142900 Replicon chromosome
Accession NZ_CP036273
Organism Urbifossiella limnaea strain ETA_A1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ETAA1_RS00650 Protein ID WP_145233388.1
Coordinates 142553..142900 (+) Length 116 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ETAA1_RS00645 Protein ID WP_145233387.1
Coordinates 142335..142556 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ETAA1_RS00630 137719..139308 + 1590 WP_145233382.1 hypothetical protein -
ETAA1_RS00635 139468..140067 + 600 WP_145233383.1 hypothetical protein -
ETAA1_RS31330 140511..140936 + 426 Protein_126 PPC domain-containing protein -
ETAA1_RS00645 142335..142556 + 222 WP_145233387.1 DUF433 domain-containing protein Antitoxin
ETAA1_RS00650 142553..142900 + 348 WP_145233388.1 DUF5615 family PIN-like protein Toxin
ETAA1_RS00655 142918..144303 - 1386 WP_145233389.1 ethanolamine ammonia-lyase subunit EutB -
ETAA1_RS00660 144759..145583 - 825 WP_202920991.1 IS3 family transposase -
ETAA1_RS00665 145631..145927 - 297 WP_145233393.1 transposase -
ETAA1_RS00670 145992..146636 + 645 WP_202920563.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(3-78)

Antitoxin

Protein of unknown function DUF433

(7-62)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 11802.70 Da        Isoelectric Point: 4.5899

>T119461 WP_145233388.1 NZ_CP036273:142553-142900 [Urbifossiella limnaea]
VTVWLDAHLSPALAPWLAATFGVTATAVRDLGLRDALDPPIFDAARAAGAVVMTKDADFAEMVGRLGTPPQVVWLRCGNT
SNAALRTLLTAEFPAAMAQLAAGVPLVEVGAPGVP

Download         Length: 348 bp

>T119461 NZ_CP036273:142553-142900 [Urbifossiella limnaea]
GTGACGGTCTGGCTGGATGCGCACCTGTCGCCGGCCCTGGCGCCGTGGCTGGCCGCAACGTTCGGGGTGACGGCGACGGC
CGTCCGTGACCTCGGCCTGCGCGACGCGCTCGACCCGCCGATCTTCGACGCCGCGCGGGCGGCCGGGGCAGTCGTGATGA
CGAAGGACGCCGACTTCGCGGAAATGGTCGGCCGACTCGGGACACCGCCCCAGGTGGTCTGGCTCCGGTGCGGGAACACG
TCGAACGCCGCGCTTCGGACTCTCTTGACCGCCGAGTTTCCCGCGGCGATGGCGCAACTCGCCGCGGGCGTTCCGCTCGT
CGAGGTCGGAGCCCCCGGCGTTCCCTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 7704.90 Da        Isoelectric Point: 4.5898

>AT119461 WP_145233387.1 NZ_CP036273:142335-142556 [Urbifossiella limnaea]
MVADDRITFNPLQCGGRPCVRGMRIRVSDVLDLLAAGLSHADVVAELPDLEPADVVACLRYASALTARPEAAA

Download         Length: 222 bp

>AT119461 NZ_CP036273:142335-142556 [Urbifossiella limnaea]
ATGGTGGCGGACGATCGGATCACGTTCAATCCGCTCCAGTGCGGCGGGCGGCCGTGCGTGCGCGGGATGCGCATCCGCGT
CAGCGACGTGCTCGACCTCCTCGCCGCCGGCCTGTCGCACGCCGACGTGGTCGCCGAACTGCCCGACCTCGAACCGGCCG
ACGTGGTCGCCTGCCTGCGGTACGCCAGCGCCCTCACCGCCCGGCCGGAGGCCGCCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References