119446

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4462542..4462903 Replicon chromosome
Accession NZ_CP036251
Organism Xanthomonas oryzae strain X11-5A

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag EYR27_RS20750 Protein ID WP_011257368.1
Coordinates 4462769..4462903 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag EYR27_RS20745 Protein ID WP_011407410.1
Coordinates 4462542..4462694 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EYR27_RS20715 4458105..4458799 + 695 Protein_3741 IS5 family transposase -
EYR27_RS20720 4458852..4459535 - 684 WP_019303216.1 dTMP kinase -
EYR27_RS20730 4460015..4460526 - 512 Protein_3743 GTPase -
EYR27_RS20735 4460523..4461050 - 528 WP_019303215.1 hypothetical protein -
EYR27_RS23540 4461051..4461188 - 138 WP_019303214.1 hypothetical protein -
EYR27_RS20740 4461511..4462434 + 924 WP_053507309.1 arginase -
EYR27_RS20745 4462542..4462694 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
EYR27_RS20750 4462769..4462903 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
EYR27_RS20755 4463144..4463353 + 210 WP_019302520.1 CsbD family protein -
EYR27_RS20760 4463522..4464811 + 1290 WP_019302519.1 tryptophan--tRNA ligase -
EYR27_RS20765 4464864..4465886 + 1023 WP_193556589.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T119446 WP_011257368.1 NZ_CP036251:4462769-4462903 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T119446 NZ_CP036251:4462769-4462903 [Xanthomonas oryzae]
ATGAAGCGTGCAATTGTGTTGCTGGTGCTGTCGATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
GGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGAAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT119446 WP_011407410.1 NZ_CP036251:4462542-4462694 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT119446 NZ_CP036251:4462542-4462694 [Xanthomonas oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References