Detailed information of TA system TA119445

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 3419052..3420556
• Replicon: chromosome
• Accession: NZ_CP036251
• Organism: Xanthomonas oryzae strain X11-5A

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: EYR27_RS15665
• Protein ID: WP_202976887.1
• Coordinates: 3419052..3419486 (+)
• Length: 145 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: A0A0M1KK33
• Locus tag: EYR27_RS15670
• Protein ID: WP_019300537.1
• Coordinates: 3419486..3420556 (+)
• Length: 357 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EYR27_RS15640	3414267..3415058	-	792	WP_029217955.1	polysaccharide deacetylase family protein	-
EYR27_RS15645	3415104..3416030	+	927	WP_019303351.1	Grx4 family monothiol glutaredoxin	-
EYR27_RS15650	3416305..3417288	+	984	WP_132709665.1	IS5 family transposase	-
EYR27_RS23590	3417477..3417869	+	393	WP_202976886.1	DUF4433 domain-containing protein	-
EYR27_RS15660	3417778..3419043	+	1266	WP_132709758.1	IS4 family transposase	-
EYR27_RS15665	3419052..3419486	+	435	WP_202976887.1	DUF4433 domain-containing protein	Toxin
EYR27_RS15670	3419486..3420556	+	1071	WP_019300537.1	macro domain-containing protein	Antitoxin
EYR27_RS15675	3420663..3421223	-	561	WP_019300536.1	DUF924 family protein	-
EYR27_RS15680	3421363..3422772	+	1410	Protein_2823	amidohydrolase	-
EYR27_RS15685	3422769..3424050	+	1282	Protein_2824	amidohydrolase family protein	-
EYR27_RS15690	3424413..3424694	+	282	WP_050543796.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (1-144)

Antitoxin

• Macro domain (18-130)

Sequences

Toxin

Protein

• Length: 145 a.a.
• Molecular weight: 16828.22 Da
• Isoelectric Point: 6.8702

>T119445 WP_202976887.1 NZ_CP036251:3419052-3419486 [Xanthomonas oryzae]
VPFYFTPFSPMLRNINTGWGGIQRRTNEEIVILVSGLHHVAARGWSFLFTDSHAYYQLTNLYSDLANLDKIDWPLLQARD
SRRDQEDPAKFERYQAEALVYRHLPVDGLLGIVCYTDDMKVSIELQLKARKLALPVYARTEWYF

Nucleotide

• Length: 435 bp

>T119445 NZ_CP036251:3419052-3419486 [Xanthomonas oryzae]
GTGCCTTTCTACTTCACTCCATTTTCGCCCATGCTGCGCAACATCAATACCGGCTGGGGAGGTATCCAACGACGGACGAA
CGAAGAGATCGTGATACTTGTTTCTGGCCTCCACCATGTCGCAGCGCGAGGATGGTCTTTCTTGTTCACCGATAGCCACG
CTTACTATCAGTTAACAAATCTCTATTCCGACTTGGCAAATCTGGACAAGATTGACTGGCCATTGCTACAGGCGCGCGAT
TCTCGGCGCGATCAAGAGGACCCGGCGAAGTTCGAGCGATATCAAGCAGAAGCGCTGGTTTACCGACACTTGCCGGTCGA
TGGCCTGCTTGGCATCGTGTGTTATACGGACGATATGAAAGTCTCTATCGAACTTCAGCTCAAGGCTCGCAAGCTTGCAC
TTCCCGTTTATGCCCGCACCGAGTGGTACTTCTGA

Antitoxin

Protein

• Length: 357 a.a.
• Molecular weight: 40232.42 Da
• Isoelectric Point: 6.1680

>AT119445 WP_019300537.1 NZ_CP036251:3419486-3420556 [Xanthomonas oryzae]
MITFTQGNLLQARVEALVNTVNTVGVMGKGIALMFKERFNENFLRYAAACKAKQVRTGKMFVTEANELNGPRWIINFPTK
QHWRGDSRIEWIAEGLQDLRFFLIENNVESIAIPPLGAGNGGLDWADVRPLIEESLTGLDTKILVFEPISKYQNVAKRSG
VEKLTPARALIAELVRRYWVLGMECSLLEIQTLAWFLERNIERAGLPTMDLRFAPHKYGPYADRLRHLLNGLDGSYLHCD
KRIGDADPLDIIWFDDARKSFLQAYLKSEAKEYAPVLEATAALIDGFESPFGMELLATIDWLIAQADVSPQLANMREGIR
RWPGGPEAAMRKDRLFDDRALSIALERLTSSVNMVF

Nucleotide

• Length: 1071 bp

>AT119445 NZ_CP036251:3419486-3420556 [Xanthomonas oryzae]
ATGATTACGTTCACGCAAGGCAATTTGCTGCAGGCACGCGTAGAGGCGTTGGTCAATACAGTCAATACTGTCGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGCTTCAACGAAAATTTCCTCCGATATGCTGCTGCCTGTAAGGCAAAGC
AAGTACGCACCGGCAAGATGTTCGTCACGGAAGCCAACGAGCTGAATGGACCACGCTGGATCATAAACTTCCCGACAAAG
CAGCACTGGCGTGGTGATTCGCGCATCGAATGGATTGCTGAGGGCCTGCAGGATCTGCGCTTCTTTCTGATCGAAAATAA
TGTCGAGTCGATTGCCATCCCGCCACTGGGCGCTGGCAATGGCGGCTTGGACTGGGCTGATGTTCGTCCACTGATAGAAG
AATCGCTGACTGGTTTAGATACCAAGATTCTTGTGTTCGAACCGATTTCGAAGTACCAAAACGTCGCAAAGCGCTCCGGC
GTGGAGAAGCTCACTCCGGCACGCGCATTGATTGCCGAACTGGTGCGTCGCTATTGGGTGTTAGGCATGGAATGCAGCCT
ACTTGAAATCCAGACGCTGGCATGGTTCCTTGAACGCAACATCGAGCGCGCAGGCTTACCCACCATGGATTTGCGCTTTG
CGCCACACAAGTACGGACCATATGCCGATCGTCTCCGCCATCTACTGAACGGACTCGATGGCAGCTATCTGCACTGTGAC
AAACGAATCGGCGACGCTGACCCACTAGATATCATCTGGTTCGATGATGCTCGCAAAAGCTTTCTCCAAGCATATCTCAA
GAGCGAAGCTAAAGAGTACGCCCCGGTACTAGAAGCCACCGCAGCCTTAATTGATGGTTTTGAATCCCCTTTTGGCATGG
AGTTACTGGCAACGATTGACTGGCTAATTGCGCAAGCAGATGTCTCCCCGCAATTAGCGAACATGCGCGAGGGGATACGC
CGCTGGCCTGGTGGCCCAGAAGCAGCCATGCGAAAAGACAGACTGTTCGATGACCGCGCTCTAAGCATCGCTTTAGAACG
ACTAACATCAAGTGTAAACATGGTATTTTGA

Structures

Antitoxin

• AlphaFold DB: A0A0M1KK33