Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-YefM
Location 2837074..2837615 Replicon chromosome
Accession NZ_CP036250
Organism Egicoccus halophilus strain EGI 80432

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ELR47_RS12790 Protein ID WP_130650251.1
Coordinates 2837074..2837334 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ELR47_RS12795 Protein ID WP_130650252.1
Coordinates 2837334..2837615 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELR47_RS18405 2832156..2833340 - 1185 WP_165404059.1 hypothetical protein -
ELR47_RS12775 2833337..2834908 - 1572 WP_130650248.1 S-layer homology domain-containing protein -
ELR47_RS12780 2835281..2836111 + 831 WP_130650249.1 thioesterase family protein -
ELR47_RS12785 2836460..2837017 + 558 WP_130650250.1 hypothetical protein -
ELR47_RS12790 2837074..2837334 - 261 WP_130650251.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
ELR47_RS12795 2837334..2837615 - 282 WP_130650252.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ELR47_RS12800 2837738..2838643 + 906 WP_130650253.1 tyrosine-type recombinase/integrase -
ELR47_RS12805 2838747..2839091 - 345 WP_130650254.1 hypothetical protein -
ELR47_RS12810 2839354..2839893 - 540 WP_130650255.1 hypothetical protein -
ELR47_RS12815 2840814..2841305 + 492 WP_130650256.1 hypothetical protein -
ELR47_RS18410 2841567..2841716 + 150 WP_165404060.1 hypothetical protein -
ELR47_RS12820 2841748..2842155 - 408 WP_165404061.1 helix-turn-helix domain-containing protein -
ELR47_RS12825 2842152..2842364 - 213 WP_130650258.1 type II toxin-antitoxin system HicA family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(25-77)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9898.33 Da        Isoelectric Point: 9.9108

>T119443 WP_130650251.1 NZ_CP036250:c2837334-2837074 [Egicoccus halophilus]
VARVFLTRIAREALAALDYLRADAVLDALGELERDPHIGHELRGRLTGLRSYRVGVYRIIYEIRDDRTVRVVAIRHRGNA
YEADPR

Download         Length: 261 bp

>T119443 NZ_CP036250:c2837334-2837074 [Egicoccus halophilus]
GTGGCACGGGTCTTCCTCACCCGCATCGCGCGGGAGGCCTTGGCCGCGCTCGACTACCTGCGCGCTGACGCGGTTCTGGA
TGCGCTCGGTGAGCTCGAACGCGATCCGCACATCGGCCACGAGCTACGCGGACGGCTCACCGGGCTTCGGTCCTACCGGG
TCGGCGTCTACCGCATCATCTACGAGATCCGAGACGACCGCACCGTGCGCGTGGTCGCCATCCGGCACCGCGGCAACGCC
TACGAGGCAGACCCGCGATAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10413.63 Da        Isoelectric Point: 4.4587

>AT119443 WP_130650252.1 NZ_CP036250:c2837615-2837334 [Egicoccus halophilus]
MPKTVPVREFRTHLAELLDEVADRREHVTVTRRGRPAAVLVPVDEYEALEETAEILSDEPTLDAIRRGLDDLAAGEVVSL
DEVRAEHAARDRS

Download         Length: 282 bp

>AT119443 NZ_CP036250:c2837615-2837334 [Egicoccus halophilus]
ATGCCGAAGACCGTGCCTGTCCGTGAGTTCCGCACCCACCTCGCCGAGCTGCTCGACGAGGTGGCTGACCGTCGTGAGCA
CGTCACCGTCACACGACGTGGCCGACCCGCAGCGGTGCTGGTCCCGGTCGACGAGTACGAAGCACTGGAGGAGACGGCCG
AGATCCTCTCCGACGAGCCCACGCTCGACGCGATCCGCCGCGGTCTCGACGACCTGGCGGCCGGCGAGGTTGTCTCGCTG
GACGAGGTCCGTGCCGAGCACGCCGCCCGTGACCGCTCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References