Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/YafQ-RelB |
Location | 486363..486899 | Replicon | chromosome |
Accession | NZ_CP036246 | ||
Organism | [Arcobacter] porcinus strain CCUG 56899 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | APORC_RS02585 | Protein ID | WP_066177392.1 |
Coordinates | 486624..486899 (+) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | APORC_RS02580 | Protein ID | WP_066177388.1 |
Coordinates | 486363..486623 (+) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
APORC_RS02555 | 482470..483681 | - | 1212 | WP_066387778.1 | TolC family protein | - |
APORC_RS02560 | 483829..484260 | + | 432 | WP_066171849.1 | TonB-system energizer ExbB | - |
APORC_RS02565 | 484241..484618 | + | 378 | WP_066171850.1 | biopolymer transporter ExbD | - |
APORC_RS02570 | 484622..485287 | + | 666 | WP_066387783.1 | energy transducer TonB | - |
APORC_RS02575 | 485328..486251 | - | 924 | WP_066171854.1 | transporter | - |
APORC_RS02580 | 486363..486623 | + | 261 | WP_066177388.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
APORC_RS02585 | 486624..486899 | + | 276 | WP_066177392.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
APORC_RS02590 | 486922..488373 | - | 1452 | WP_066171856.1 | acetyl-CoA carboxylase biotin carboxylase subunit | - |
APORC_RS02595 | 488640..489872 | + | 1233 | WP_066387784.1 | major outer membrane protein | - |
APORC_RS02600 | 490249..491124 | + | 876 | WP_066387785.1 | ORF6N domain-containing protein | - |
APORC_RS02605 | 491211..491441 | + | 231 | WP_066387786.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10615.46 Da Isoelectric Point: 9.5188
>T119423 WP_066177392.1 NZ_CP036246:486624-486899 [[Arcobacter] porcinus]
MLDLKIHKIFTKDLKKAQLNSTNSSKLFLYISLLLNNKELPKEAKNHSLKGEWEDTMEFHISGDLIVIYIIDDISLQLLR
IGTHSQLFKKF
MLDLKIHKIFTKDLKKAQLNSTNSSKLFLYISLLLNNKELPKEAKNHSLKGEWEDTMEFHISGDLIVIYIIDDISLQLLR
IGTHSQLFKKF
Download Length: 276 bp
>T119423 NZ_CP036246:486624-486899 [[Arcobacter] porcinus]
ATGCTTGATTTAAAAATTCATAAGATATTTACAAAGGATTTAAAAAAGGCTCAGTTGAATTCAACAAACTCATCAAAACT
ATTTTTATATATTTCACTACTTCTAAACAATAAAGAATTACCAAAAGAGGCAAAAAACCACTCTTTAAAAGGCGAATGGG
AAGATACAATGGAATTTCATATAAGTGGAGATTTAATTGTAATTTATATTATAGACGATATAAGCTTACAACTTTTAAGA
ATAGGAACTCATTCACAGCTTTTTAAAAAGTTTTAA
ATGCTTGATTTAAAAATTCATAAGATATTTACAAAGGATTTAAAAAAGGCTCAGTTGAATTCAACAAACTCATCAAAACT
ATTTTTATATATTTCACTACTTCTAAACAATAAAGAATTACCAAAAGAGGCAAAAAACCACTCTTTAAAAGGCGAATGGG
AAGATACAATGGAATTTCATATAAGTGGAGATTTAATTGTAATTTATATTATAGACGATATAAGCTTACAACTTTTAAGA
ATAGGAACTCATTCACAGCTTTTTAAAAAGTTTTAA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9790.34 Da Isoelectric Point: 10.0678
>AT119423 WP_066177388.1 NZ_CP036246:486363-486623 [[Arcobacter] porcinus]
MTTTSNKIRTNVYLDSTTKQKAQEIFKQYGLGLSEAFNIFLTQSVLEKGIPFEIKIPNEKTIEAIKDARANKNIKKVSLD
DLKKEL
MTTTSNKIRTNVYLDSTTKQKAQEIFKQYGLGLSEAFNIFLTQSVLEKGIPFEIKIPNEKTIEAIKDARANKNIKKVSLD
DLKKEL
Download Length: 261 bp
>AT119423 NZ_CP036246:486363-486623 [[Arcobacter] porcinus]
ATGACTACAACTTCAAATAAAATAAGAACAAATGTATATCTTGATTCAACTACAAAACAAAAAGCTCAAGAGATTTTTAA
ACAATATGGTTTAGGTTTGAGTGAAGCTTTCAATATTTTTTTAACACAAAGTGTTCTAGAAAAAGGAATTCCTTTTGAAA
TAAAAATTCCAAATGAAAAAACAATAGAAGCTATAAAAGATGCAAGAGCAAATAAAAATATAAAAAAAGTTAGTTTAGAT
GATTTAAAAAAAGAGTTATAG
ATGACTACAACTTCAAATAAAATAAGAACAAATGTATATCTTGATTCAACTACAAAACAAAAAGCTCAAGAGATTTTTAA
ACAATATGGTTTAGGTTTGAGTGAAGCTTTCAATATTTTTTTAACACAAAGTGTTCTAGAAAAAGGAATTCCTTTTGAAA
TAAAAATTCCAAATGAAAAAACAATAGAAGCTATAAAAGATGCAAGAGCAAATAAAAATATAAAAAAAGTTAGTTTAGAT
GATTTAAAAAAAGAGTTATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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