Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 95190..95335 Replicon chromosome
Accession NZ_CP036190
Organism Klebsiella pneumoniae strain BA34918

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 95226..95328 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 95190..95335 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EX353_RS00440 90320..92380 + 2061 WP_130627726.1 oligopeptidase B -
EX353_RS00445 92384..93043 - 660 WP_002911407.1 exodeoxyribonuclease X -
EX353_RS00450 93122..93352 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EX353_RS00455 93465..93839 + 375 WP_004151448.1 CopC domain-containing protein YobA -
EX353_RS00460 93843..94712 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
EX353_RS00465 94729..95067 + 339 WP_002911404.1 YebY family protein -
- 95190..95335 - 146 - - Antitoxin
- 95226..95328 + 103 - - Toxin
EX353_RS31485 95704..95847 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EX353_RS00475 95952..96920 - 969 WP_014907334.1 VirK/YbjX family protein -
EX353_RS00480 97077..97730 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
EX353_RS00485 97727..97918 - 192 WP_002911395.1 YebW family protein -
EX353_RS00490 98016..98255 - 240 WP_002911393.1 YebV family protein -
EX353_RS00495 98371..99804 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T119311 NZ_CP036190:95226-95328 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT119311 NZ_CP036190:c95335-95190 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References