Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc(toxin)
Location 911079..911650 Replicon chromosome
Accession NZ_CP036186
Organism Pseudomonas stutzeri strain ATCC 14405

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag Pstu14405_RS04115 Protein ID WP_036991553.1
Coordinates 911249..911650 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag Pstu14405_RS04110 Protein ID WP_082332108.1
Coordinates 911079..911249 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Pstu14405_RS04080 906098..906688 - 591 WP_003283174.1 malonic semialdehyde reductase -
Pstu14405_RS04085 906699..907496 - 798 WP_003283175.1 pyrimidine utilization protein D -
Pstu14405_RS04090 907562..907948 - 387 WP_003283176.1 pyrimidine utilization protein C -
Pstu14405_RS04095 908028..908774 - 747 WP_003283178.1 pyrimidine utilization protein B -
Pstu14405_RS04100 908774..909856 - 1083 WP_003283180.1 pyrimidine utilization protein A -
Pstu14405_RS04105 910139..910849 + 711 WP_036991550.1 HTH-type transcriptional regulator RutR -
Pstu14405_RS04110 911079..911249 + 171 WP_082332108.1 acetyltransferase Antitoxin
Pstu14405_RS04115 911249..911650 + 402 WP_036991553.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
Pstu14405_RS04120 911683..912864 - 1182 WP_003283184.1 MFS transporter -
Pstu14405_RS04125 912957..913946 - 990 WP_003283185.1 GlxA family transcriptional regulator -
Pstu14405_RS04130 914287..915411 + 1125 WP_003283187.1 alkene reductase -
Pstu14405_RS04135 915496..915801 + 306 WP_003283189.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(1-129)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14591.45 Da        Isoelectric Point: 3.9138

>T119288 WP_036991553.1 NZ_CP036186:911249-911650 [Pseudomonas stutzeri]
MNLIFFPFERVVEINSFILVHEPGMKGSVDIGKLQGALGRIDNAIAYEGLDDVFEIAAKYAACISVAHSLPDANKRTALA
VALEYLSLNDYELSEDNELFADALRDLVLGVINEGDFADLLYAQYVQEAESST

Download         Length: 402 bp

>T119288 NZ_CP036186:911249-911650 [Pseudomonas stutzeri]
ATGAATTTGATTTTCTTTCCGTTCGAACGGGTTGTTGAAATAAACTCATTCATTCTTGTGCATGAACCTGGAATGAAAGG
TTCGGTTGATATCGGCAAGCTTCAGGGTGCCTTGGGACGTATCGATAACGCAATCGCTTATGAAGGGTTGGATGATGTAT
TTGAGATTGCGGCAAAATATGCGGCCTGCATATCGGTGGCGCACTCATTGCCTGACGCAAACAAGCGAACCGCGCTCGCA
GTCGCATTGGAGTACCTTTCATTGAACGACTATGAATTGAGCGAAGATAATGAACTCTTTGCGGATGCGTTAAGGGACCT
GGTGCTGGGCGTTATTAACGAAGGGGACTTTGCTGACTTGCTCTATGCTCAATATGTTCAGGAAGCCGAGTCCAGTACAT
AG

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6371.64 Da        Isoelectric Point: 11.1577

>AT119288 WP_082332108.1 NZ_CP036186:911079-911249 [Pseudomonas stutzeri]
MNRKIEAYGVKAVKRPKIQAVKFLDLSGISGQQIVKSETKLVLRTHKQTFKKLADM

Download         Length: 171 bp

>AT119288 NZ_CP036186:911079-911249 [Pseudomonas stutzeri]
ATGAACAGAAAAATTGAAGCTTACGGAGTTAAGGCTGTAAAACGACCTAAGATCCAAGCGGTGAAGTTTCTTGATCTATC
GGGAATATCCGGGCAACAGATCGTCAAGTCTGAAACGAAACTAGTCCTAAGAACACATAAGCAGACTTTTAAAAAGTTGG
CTGATATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References