Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2023602..2023873 Replicon chromosome
Accession NZ_CP036177
Organism Escherichia coli strain WCHEC025970

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2023732..2023835 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2023602..2023873 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EYD11_RS09770 2020157..2020819 - 663 WP_000944256.1 exodeoxyribonuclease X -
EYD11_RS09775 2020843..2021499 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EYD11_RS09780 2021601..2021831 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EYD11_RS09785 2021970..2022344 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EYD11_RS09790 2022348..2023220 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
EYD11_RS09795 2023233..2023574 + 342 WP_000976476.1 YebY family protein -
- 2023602..2023873 - 272 - - Antitoxin
- 2023732..2023835 + 104 - - Toxin
EYD11_RS09800 2023970..2024626 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
EYD11_RS09805 2024627..2024818 - 192 WP_000457842.1 YebW family protein -
EYD11_RS09810 2024923..2025159 - 237 WP_001295499.1 DUF1480 family protein -
EYD11_RS09815 2025277..2026716 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T119262 NZ_CP036177:2023732-2023835 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT119262 NZ_CP036177:c2023873-2023602 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References