Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 979941..980598 Replicon chromosome
Accession NZ_CP036175
Organism Klebsiella huaxiensis strain WCHKl090001

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag DA718_RS04765 Protein ID WP_110276702.1
Coordinates 980188..980598 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag DA718_RS04760 Protein ID WP_112216528.1
Coordinates 979941..980207 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DA718_RS04745 975111..975536 - 426 WP_112216531.1 PTS sugar transporter subunit IIA -
DA718_RS04750 975657..978455 - 2799 WP_112216530.1 transcriptional regulator DagR -
DA718_RS04755 978714..979697 - 984 WP_112216529.1 tRNA-modifying protein YgfZ -
DA718_RS04760 979941..980207 + 267 WP_112216528.1 FAD assembly factor SdhE Antitoxin
DA718_RS04765 980188..980598 + 411 WP_110276702.1 protein YgfX Toxin
DA718_RS04770 980607..981128 - 522 WP_112216527.1 flavodoxin FldB -
DA718_RS04775 981250..982146 + 897 WP_112216526.1 site-specific tyrosine recombinase XerD -
DA718_RS04780 982170..982883 + 714 WP_112216525.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
DA718_RS04785 982889..984622 + 1734 WP_112216524.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-77)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16076.91 Da        Isoelectric Point: 11.0688

>T119238 WP_110276702.1 NZ_CP036175:980188-980598 [Klebsiella huaxiensis]
VVLWQSDLRISWRAQWFSLLLHGVVAALVLLMPWPLSYTPLWLILLSLVVFDCVRSQRRIHARQGEIKLLMDSRLRWQKA
EWEIVGTPWVINSGMLLRLRDTKNHRTQHLWVAADSMDAGEWRDLRRLVLQKSAQD

Download         Length: 411 bp

>T119238 NZ_CP036175:980188-980598 [Klebsiella huaxiensis]
GTGGTCCTGTGGCAATCTGATTTACGCATCTCATGGCGAGCGCAGTGGTTCTCACTACTGCTGCACGGCGTTGTGGCGGC
ACTCGTGCTGCTGATGCCCTGGCCGCTCAGCTACACCCCGTTATGGCTGATACTGCTGTCGCTGGTGGTGTTTGATTGCG
TGCGCAGCCAGAGGCGGATTCACGCCCGTCAGGGCGAAATAAAACTGCTGATGGACTCCCGACTGCGCTGGCAAAAAGCG
GAGTGGGAAATCGTCGGTACCCCATGGGTGATCAATAGCGGAATGCTGTTGCGTCTGCGGGATACAAAAAACCACCGTAC
CCAGCATCTGTGGGTTGCGGCAGATAGTATGGACGCGGGAGAGTGGCGCGACCTGCGCCGACTGGTGTTACAGAAATCGG
CGCAAGATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10510.08 Da        Isoelectric Point: 4.8432

>AT119238 WP_112216528.1 NZ_CP036175:979941-980207 [Klebsiella huaxiensis]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDGDKLLFIRLLENDDPDLFNWLMNHGEPADAEMQRMVKLIQIRN
RERGPVAI

Download         Length: 267 bp

>AT119238 NZ_CP036175:979941-980207 [Klebsiella huaxiensis]
ATGGATATTAACAATAAAGCTCGTATCCACTGGGCGTGTCGCCGGGGGATGCGTGAACTCGATATCTCCATCATGCCGTT
TTTTGAGTACGAGTACGATACGCTCAGCGATGGCGACAAGCTGTTGTTCATCCGCCTGCTGGAAAACGACGATCCGGATC
TGTTCAACTGGTTAATGAACCATGGCGAACCGGCTGATGCGGAAATGCAACGGATGGTAAAATTAATTCAGATACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References