Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 3058927..3059479 Replicon chromosome
Accession NZ_CP036164
Organism Janibacter limosus strain P3-3-X1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag EXU32_RS14670 Protein ID WP_130630574.1
Coordinates 3059165..3059479 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag EXU32_RS14665 Protein ID WP_130630573.1
Coordinates 3058927..3059160 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EXU32_RS14650 3054992..3055771 - 780 WP_130630570.1 fructosamine kinase family protein -
EXU32_RS14655 3056024..3057499 - 1476 WP_130630571.1 NAD-dependent malic enzyme -
EXU32_RS14660 3057650..3058864 + 1215 WP_130630572.1 ATP-binding protein -
EXU32_RS14665 3058927..3059160 + 234 WP_130630573.1 ribbon-helix-helix domain-containing protein Antitoxin
EXU32_RS14670 3059165..3059479 + 315 WP_130630574.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
EXU32_RS14675 3059485..3060522 + 1038 WP_130630575.1 alcohol dehydrogenase catalytic domain-containing protein -
EXU32_RS14680 3060621..3062384 + 1764 WP_130630576.1 long-chain fatty acid--CoA ligase -
EXU32_RS14685 3062541..3063731 - 1191 WP_165399698.1 HNH endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-92)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11055.88 Da        Isoelectric Point: 6.2863

>T119233 WP_130630574.1 NZ_CP036164:3059165-3059479 [Janibacter limosus]
VREICLVRLDKTRPALVLTRETARGAMTKVTVAPITTTAKGLSSEMRVGRANGLDAECAVALDNVVTVPVELLGRTVGYL
SSTQEAELARAVVMAYDLELPLTG

Download         Length: 315 bp

>T119233 NZ_CP036164:3059165-3059479 [Janibacter limosus]
GTGCGAGAGATCTGCCTGGTGCGTCTGGACAAGACCCGGCCAGCGCTCGTGCTGACCCGTGAGACCGCCCGCGGGGCGAT
GACCAAGGTGACTGTCGCGCCCATCACGACGACCGCCAAGGGGCTGTCGAGCGAGATGCGAGTCGGCCGGGCCAACGGCC
TCGATGCCGAGTGCGCCGTGGCTCTGGACAACGTCGTCACCGTCCCGGTGGAGCTGCTCGGGCGCACCGTCGGTTATCTG
TCGAGCACACAAGAGGCCGAGCTCGCACGCGCTGTGGTCATGGCCTACGACCTGGAGCTGCCGCTGACAGGATGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8374.43 Da        Isoelectric Point: 4.3304

>AT119233 WP_130630573.1 NZ_CP036164:3058927-3059160 [Janibacter limosus]
MSTQIAVRLPDEMVEFLDRSVARGEAPSRAALVTSALEREMRRLAAEHDVAVLTERGTADDLDVVVEWTAAHVAVGD

Download         Length: 234 bp

>AT119233 NZ_CP036164:3058927-3059160 [Janibacter limosus]
ATGAGCACCCAGATCGCCGTCCGCCTTCCCGACGAGATGGTCGAGTTCCTCGACCGCTCCGTCGCGAGGGGCGAGGCACC
CAGCCGCGCAGCACTGGTGACGTCTGCGCTGGAGCGAGAGATGCGCCGCCTGGCGGCTGAGCATGACGTTGCCGTCCTCA
CCGAGCGTGGCACGGCGGACGATCTCGACGTCGTGGTCGAGTGGACCGCTGCCCACGTCGCCGTCGGGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References