Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1784384..1784946 Replicon chromosome
Accession NZ_CP036164
Organism Janibacter limosus strain P3-3-X1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag EXU32_RS08580 Protein ID WP_130629524.1
Coordinates 1784617..1784946 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag EXU32_RS08575 Protein ID WP_130629523.1
Coordinates 1784384..1784620 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EXU32_RS08555 1780177..1782270 - 2094 WP_130629519.1 heavy metal translocating P-type ATPase -
EXU32_RS08560 1782347..1782799 + 453 WP_130629520.1 hypothetical protein -
EXU32_RS08565 1782891..1783535 + 645 WP_130629521.1 DUF305 domain-containing protein -
EXU32_RS08570 1783683..1784387 + 705 WP_130629522.1 hypothetical protein -
EXU32_RS08575 1784384..1784620 + 237 WP_130629523.1 DUF2191 domain-containing protein Antitoxin
EXU32_RS08580 1784617..1784946 + 330 WP_130629524.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
EXU32_RS08585 1784984..1785355 + 372 WP_130629525.1 metalloregulator ArsR/SmtB family transcription factor -
EXU32_RS08590 1785352..1786314 + 963 WP_130629526.1 cation diffusion facilitator family transporter -
EXU32_RS08595 1786443..1787594 + 1152 WP_130629527.1 helix-turn-helix domain-containing protein -
EXU32_RS08600 1787584..1788807 - 1224 WP_130629528.1 FAD-dependent monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-104)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 11762.73 Da        Isoelectric Point: 6.9037

>T119231 WP_130629524.1 NZ_CP036164:1784617-1784946 [Janibacter limosus]
MTALPARGEVWWCEMAGIGRRPVVVLSRDSVIPRLRRSLVAPCTTTIRALASEVHLEPGEDPIPLRSAVNLDSVESVSVA
VLIERIGRLSDARMREVCAALAIAVDCSS

Download         Length: 330 bp

>T119231 NZ_CP036164:1784617-1784946 [Janibacter limosus]
ATGACGGCGCTACCCGCTCGGGGTGAGGTGTGGTGGTGCGAGATGGCCGGGATCGGGCGAAGACCCGTCGTCGTGCTCTC
CCGCGACTCGGTCATCCCGCGTCTACGCCGATCCCTTGTGGCCCCGTGCACGACGACGATCCGCGCTCTGGCGAGCGAGG
TCCACCTTGAGCCGGGCGAGGACCCCATCCCCCTGCGCTCGGCCGTCAACCTGGACTCGGTGGAGAGCGTCTCCGTCGCC
GTCCTCATCGAACGGATCGGCCGCTTGTCGGATGCGCGCATGCGCGAAGTGTGTGCGGCTCTCGCGATCGCGGTCGACTG
CTCGTCCTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8388.30 Da        Isoelectric Point: 4.4067

>AT119231 WP_130629523.1 NZ_CP036164:1784384-1784620 [Janibacter limosus]
MTRTRLSTTVDAELLASARGALPGLTDAKMLDEALSALVTRHRAAEIEAGYVAYDDHPLDEPDAWGDLASFREAASRS

Download         Length: 237 bp

>AT119231 NZ_CP036164:1784384-1784620 [Janibacter limosus]
ATGACTAGAACACGACTCAGCACGACCGTCGACGCCGAGCTGCTCGCCAGTGCTCGCGGCGCCCTCCCCGGGCTCACGGA
CGCCAAGATGCTCGATGAGGCTCTGTCGGCCCTCGTCACGCGTCACCGCGCTGCCGAGATCGAGGCCGGCTATGTCGCGT
ATGACGATCACCCACTTGATGAGCCGGATGCCTGGGGTGATCTCGCATCCTTCCGCGAAGCCGCTAGCCGATCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References