Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpIK/MazF(toxin)
Location 3213437..3214007 Replicon chromosome
Accession NZ_CP036150
Organism Oceanispirochaeta crateris strain K2

Toxin (Protein)


Gene name chpK Uniprot ID -
Locus tag EXM22_RS14615 Protein ID WP_149487229.1
Coordinates 3213437..3213778 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name chpI Uniprot ID -
Locus tag EXM22_RS14620 Protein ID WP_149487230.1
Coordinates 3213765..3214007 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EXM22_RS14605 3211219..3211815 - 597 WP_149487227.1 DUF4194 domain-containing protein -
EXM22_RS14610 3211802..3213262 - 1461 WP_149487228.1 DUF3375 domain-containing protein -
EXM22_RS14615 3213437..3213778 - 342 WP_149487229.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
EXM22_RS14620 3213765..3214007 - 243 WP_149487230.1 ChpI protein Antitoxin
EXM22_RS14625 3214108..3215016 - 909 WP_149487231.1 IS3 family transposase -
EXM22_RS14630 3214971..3215279 - 309 WP_210411499.1 transposase -
EXM22_RS14635 3215566..3215823 - 258 WP_168203534.1 integrase core domain-containing protein -
EXM22_RS14640 3215792..3216337 - 546 WP_149487233.1 ATP-binding protein -
EXM22_RS14645 3216334..3216726 - 393 WP_149487234.1 hypothetical protein -
EXM22_RS14650 3217042..3217350 - 309 WP_168203535.1 transposase -
EXM22_RS14655 3217447..3218596 - 1150 Protein_2879 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-109)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12655.74 Da        Isoelectric Point: 4.8146

>T119230 WP_149487229.1 NZ_CP036150:c3213778-3213437 [Oceanispirochaeta crateris]
MIRGEIWWVDLGIPFGSEPGYKRPVVVIQEDSFNKSRIQTVIVASVTSNLSLADAPGNVYLEKEESKLPKDSVINISQIV
TLDKQRLIEKAAILPSTLMIEVDYGLRIILNMQ

Download         Length: 342 bp

>T119230 NZ_CP036150:c3213778-3213437 [Oceanispirochaeta crateris]
ATGATACGTGGTGAAATATGGTGGGTTGATTTAGGAATCCCCTTTGGAAGTGAGCCCGGTTATAAAAGACCTGTTGTCGT
AATCCAGGAAGATTCTTTCAATAAAAGCAGAATACAAACAGTAATAGTAGCATCTGTCACTTCAAACCTAAGTTTAGCAG
ATGCTCCGGGTAACGTTTATCTGGAAAAAGAAGAATCTAAATTACCAAAAGACAGCGTTATAAATATTTCTCAAATAGTT
ACTTTAGATAAACAGCGCTTAATTGAAAAAGCGGCAATTCTACCTTCAACTTTGATGATTGAAGTTGATTATGGATTAAG
AATCATTCTGAATATGCAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9217.29 Da        Isoelectric Point: 4.7914

>AT119230 WP_149487230.1 NZ_CP036150:c3214007-3213765 [Oceanispirochaeta crateris]
MKTAISIPDQLFNEAEVTAKQLGLARSQLYVKAIKEFIEHHNKDRITEKLNDIYSVQNDDNDLSNIGVEQLRKATENDTW

Download         Length: 243 bp

>AT119230 NZ_CP036150:c3214007-3213765 [Oceanispirochaeta crateris]
ATGAAAACAGCTATATCCATACCAGATCAGTTATTTAATGAGGCTGAAGTCACAGCGAAACAGCTAGGATTGGCCAGAAG
TCAACTTTATGTGAAAGCCATAAAAGAGTTTATTGAACATCATAATAAGGACAGAATAACTGAAAAGTTGAATGATATTT
ATTCCGTCCAGAATGATGACAATGATTTATCCAATATCGGAGTAGAACAATTAAGAAAGGCCACAGAAAATGATACGTGG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References