Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2397738..2398716 Replicon chromosome
Accession NZ_CP035984
Organism Bacillus mycoides strain BPN211

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag EXW26_RS12180 Protein ID WP_201065725.1
Coordinates 2397738..2398478 (+) Length 247 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag EXW26_RS12185 Protein ID WP_215552300.1
Coordinates 2398591..2398716 (+) Length 42 a.a.

Genomic Context

EXW26_RS12155EXW26_RS12160EXW26_RS12170EXW26_RS12175EXW26_RS12180EXW26_RS12185EXW26_RS12190EXW26_RS12200EXW26_RS12205EXW26_RS12210EXW26_RS29480EXW26_RS12165EXW26_RS12195
Location: 2393727..2394437 (711 bp)
Type: Others
Protein ID: WP_215552302.1
Location: 2394557..2394970 (414 bp)
Type: Others
Protein ID: WP_215552301.1
Location: 2396053..2396529 (477 bp)
Type: Others
Protein ID: WP_002017049.1
Location: 2396683..2397420 (738 bp)
Type: Others
Protein ID: WP_002032137.1
Location: 2397738..2398478 (741 bp)
Type: Toxin
Protein ID: WP_201065725.1
Location: 2398591..2398716 (126 bp)
Type: Antitoxin
Protein ID: WP_215552300.1
Location: 2398792..2398968 (177 bp)
Type: Others
Protein ID: WP_002017052.1
Location: 2399627..2401096 (1470 bp)
Type: Others
Protein ID: WP_215552299.1
Location: 2401456..2401605 (150 bp)
Type: Others
Protein ID: WP_002069316.1
Location: 2402361..2403020 (660 bp)
Type: Others
Protein ID: WP_215552298.1
Location: 2403215..2403363 (149 bp)
Type: Others
Protein ID: Protein_2342
Location: 2395147..2395779 (633 bp)
Type: Others
Protein ID: WP_002017047.1
Location: 2398988..2399356 (369 bp)
Type: Others
Protein ID: WP_215553103.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EXW26_RS12155 (EXW26_12410)2393727..2394437+711WP_215552302.1class I SAM-dependent methyltransferase-
EXW26_RS12160 (EXW26_12415)2394557..2394970+414WP_215552301.1VOC family protein-
EXW26_RS12165 (EXW26_12420)2395147..2395779-633WP_002017047.1type 1 glutamine amidotransferase family protein-
EXW26_RS12170 (EXW26_12425)2396053..2396529+477WP_002017049.1MarR family winged helix-turn-helix transcriptional regulator-
EXW26_RS12175 (EXW26_12430)2396683..2397420+738WP_002032137.12,3-diphosphoglycerate-dependent phosphoglycerate mutase-
EXW26_RS12180 (EXW26_12435)2397738..2398478+741WP_201065725.1type II toxin-antitoxin system SpoIISA family toxinToxin
EXW26_RS12185 (EXW26_12440)2398591..2398716+126WP_215552300.1D-alanyl-D-alanine carboxypeptidaseAntitoxin
EXW26_RS121902398792..2398968+177WP_002017052.1stage II sporulation protein SB-
EXW26_RS12195 (EXW26_12445)2398988..2399356-369WP_215553103.1YxeA family protein-
EXW26_RS12200 (EXW26_12450)2399627..2401096+1470WP_215552299.1aminoacyl-histidine dipeptidase-
EXW26_RS122052401456..2401605+150WP_002069316.1hypothetical protein-
EXW26_RS12210 (EXW26_12455)2402361..2403020+660WP_215552298.1CatB-related O-acetyltransferase-
EXW26_RS294802403215..2403363+149Protein_2342bacitracin ABC transporter ATP-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(10-244)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 247 a.a.        Molecular weight: 28509.14 Da        Isoelectric Point: 8.3034

>T119139 WP_201065725.1 NZ_CP035984:2397738-2398478 [Bacillus mycoides]
MTISNIRIGLFILAIVFIVLVFFYWRNEELYEEKKQRIRKTWYGLFITSVTVYFTIKGIDLTLWKNLLMFTAMVIFVDIA
FILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPTAFGTMEWHTEEEYTKNLNTFLDSYGEKIGAK
IVVFEAVKELNTNFRGIRSQFSIIVPLEHIEQLNEQKAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIH
HSYFSK

Download         Length: 741 bp

>T119139 NZ_CP035984:2397738-2398478 [Bacillus mycoides]
TTGACGATCTCTAACATTCGAATTGGCTTATTTATTTTAGCAATCGTCTTTATTGTTCTTGTTTTCTTTTATTGGAGAAA
TGAAGAGTTGTACGAGGAGAAGAAACAACGAATTCGAAAAACGTGGTACGGTTTGTTCATAACATCAGTCACAGTTTATT
TCACGATAAAAGGAATAGATTTAACCCTCTGGAAAAATCTTTTAATGTTTACTGCGATGGTAATTTTCGTTGATATTGCA
TTCATTTTGACACCAAATATTTCAGAAATATGGGGCGCAAAATTCAGCGATATTGGAAAGACGGTCCAATCAATTAAAAG
GTCATTAATTGCTTCAAAAGCAAGAGGAGAAATATATACGACAATTATTCAAAATGTGAATCCAACAGCCTTTGGGACAA
TGGAATGGCATACGGAAGAGGAATATACAAAAAACTTAAACACATTTTTAGATTCATATGGGGAAAAGATTGGTGCGAAA
ATTGTTGTATTTGAAGCGGTGAAGGAATTAAATACAAACTTTCGTGGTATCCGCTCTCAATTTAGTATTATTGTTCCATT
AGAACATATCGAGCAATTGAATGAGCAGAAAGCGGTGCAAGTAGAAAATGTCGGAATTATACCAGCAAAAATAGTTAGTG
ATGTTTTCATTGTTATTGATGGGAAGAAAAATAACCTTCAAGATCGAGATTTTGAAAATGTATATAATTTAACAATTCAT
CATAGTTATTTTAGTAAATAA

Antitoxin


Download         Length: 42 a.a.        Molecular weight: 4939.33 Da        Isoelectric Point: 3.8705

>AT119139 WP_215552300.1 NZ_CP035984:2398591-2398716 [Bacillus mycoides]
VIKDYDNDFFKEDNEDTTDFSLIKGDTLEQVEELEEELKRK

Download         Length: 126 bp

>AT119139 NZ_CP035984:2398591-2398716 [Bacillus mycoides]
GTGATAAAAGATTATGACAATGATTTTTTTAAAGAAGATAATGAAGATACAACAGATTTCTCTTTAATAAAAGGAGATAC
TTTGGAGCAAGTAGAAGAGTTAGAAGAAGAATTAAAAAGAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References