Detailed information of TA system TA119120

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 2809654..2810150
• Replicon: chromosome
• Accession: NZ_CP035952
• Organism: Pseudomonas sp. SNU WT1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: EXN22_RS12930
• Protein ID: WP_130264423.1
• Coordinates: 2809875..2810150 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: EXN22_RS12925
• Protein ID: WP_130266814.1
• Coordinates: 2809654..2809875 (+)
• Length: 74 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EXN22_RS12915	2805024..2808203	-	3180	WP_130264421.1	efflux RND transporter permease subunit	-
EXN22_RS12920	2808216..2809457	-	1242	WP_130264422.1	efflux RND transporter periplasmic adaptor subunit	-
EXN22_RS12925	2809654..2809875	+	222	WP_130266814.1	ribbon-helix-helix protein, CopG family	Antitoxin
EXN22_RS12930	2809875..2810150	+	276	WP_130264423.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EXN22_RS12935	2810549..2810932	+	384	WP_177414017.1	hypothetical protein	-
EXN22_RS12940	2811360..2812223	+	864	WP_130264424.1	hypothetical protein	-
EXN22_RS12945	2812295..2812845	-	551	Protein_2537	transposase	-
EXN22_RS12950	2812918..2814219	-	1302	WP_177414072.1	c-type cytochrome	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2812238..2812618	380

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (1-30)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10815.48 Da
• Isoelectric Point: 7.2754

>T119120 WP_130264423.1 NZ_CP035952:2809875-2810150 [Pseudomonas sp. SNU WT1]
MQLKWTSKALSDLARLYEYLAVVNQPAEAHTVQWLATVPTTLLTNPRLCERLEEFKPRDVRRILVGHYEIRYEIADATIY
LLRMWHTREDS

Nucleotide

• Length: 276 bp

>T119120 NZ_CP035952:2809875-2810150 [Pseudomonas sp. SNU WT1]
ATGCAGTTGAAGTGGACGAGCAAGGCGCTGTCCGATCTGGCCCGACTTTACGAGTATTTGGCGGTGGTGAACCAGCCCGC
AGAGGCCCACACGGTGCAGTGGCTTGCGACAGTACCGACCACACTGCTGACTAATCCGCGCCTCTGCGAGCGCCTGGAAG
AGTTCAAACCGCGTGACGTACGGCGTATTCTGGTCGGGCACTACGAGATTCGTTACGAGATCGCAGACGCCACCATTTAC
CTGCTGCGCATGTGGCACACCCGCGAAGATAGCTAA

Antitoxin

Protein

• Length: 74 a.a.
• Molecular weight: 8411.37 Da
• Isoelectric Point: 4.4915

>AT119120 WP_130266814.1 NZ_CP035952:2809654-2809875 [Pseudomonas sp. SNU WT1]
MAERVDEIAERLERSKNWIVKQALYAWLDQEEERSRLTREALADVDAGRVIDHQAVQAWAESLSSETPLPVPH

Nucleotide

• Length: 222 bp

>AT119120 NZ_CP035952:2809654-2809875 [Pseudomonas sp. SNU WT1]
CTGGCCGAACGAGTCGATGAAATCGCCGAGCGCCTGGAACGTTCCAAGAACTGGATCGTCAAGCAAGCGCTGTACGCCTG
GCTCGACCAGGAAGAGGAGCGTAGCCGCTTGACCCGCGAGGCCCTGGCTGATGTGGATGCTGGCCGTGTGATCGACCATC
AGGCCGTCCAGGCCTGGGCTGAGAGCCTGAGCAGCGAAACCCCACTGCCGGTACCGCATTGA