Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | phd-doc/HTH_IclR(antitoxin) |
Location | 1812357..1814050 | Replicon | chromosome |
Accession | NZ_CP035952 | ||
Organism | Pseudomonas sp. SNU WT1 |
Toxin (Protein)
Gene name | doc | Uniprot ID | - |
Locus tag | EXN22_RS08390 | Protein ID | WP_130263620.1 |
Coordinates | 1813181..1814050 (-) | Length | 290 a.a. |
Antitoxin (Protein)
Gene name | phd | Uniprot ID | - |
Locus tag | EXN22_RS08385 | Protein ID | WP_130263619.1 |
Coordinates | 1812357..1813184 (-) | Length | 276 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EXN22_RS08365 | 1807565..1809055 | - | 1491 | WP_130263615.1 | aldehyde dehydrogenase | - |
EXN22_RS08370 | 1809066..1809869 | - | 804 | WP_130263616.1 | aspartate dehydrogenase | - |
EXN22_RS08375 | 1809880..1811562 | - | 1683 | WP_130263617.1 | thiamine pyrophosphate-binding protein | - |
EXN22_RS08380 | 1811555..1812355 | - | 801 | WP_130263618.1 | SDR family oxidoreductase | - |
EXN22_RS08385 | 1812357..1813184 | - | 828 | WP_130263619.1 | IclR family transcriptional regulator | Antitoxin |
EXN22_RS08390 | 1813181..1814050 | - | 870 | WP_130263620.1 | alpha/beta hydrolase | Toxin |
EXN22_RS08395 | 1814055..1814594 | - | 540 | WP_130263621.1 | cupin domain-containing protein | - |
EXN22_RS08400 | 1814610..1815374 | - | 765 | WP_130266779.1 | SDR family oxidoreductase | - |
EXN22_RS08405 | 1815374..1816150 | - | 777 | WP_130263622.1 | ABC transporter permease | - |
EXN22_RS08410 | 1816180..1817178 | - | 999 | WP_130263623.1 | ABC transporter substrate-binding protein | - |
EXN22_RS08415 | 1817218..1818069 | - | 852 | WP_130263624.1 | ABC transporter ATP-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 290 a.a. Molecular weight: 30416.70 Da Isoelectric Point: 7.0436
>T119118 WP_130263620.1 NZ_CP035952:c1814050-1813181 [Pseudomonas sp. SNU WT1]
MSHATDHSLASLKAQLQQRFTQRLVQLADGAQAIREAGHGPAIVLLHGIGSGAASWLQVALQLSPHARVIAWDAPGYGDS
SPLATPAPQAPDYARRLLQLLDALNIDDCVLVGHSLGALSAAALACQHPQRLRRLVLISPARGYGDPARAEQAQQVRSQR
LHTLEQLGIAQMAQQRGAHMLSPAASAQALGWVQWNMARLQPRGYRQAVELLCGDDLLRYAASTVPCEVHCGAADSITPP
ADCQALAAALGAPFQLIAEAGHASPIEQPEAVASLLARAIEASLTGTAL
MSHATDHSLASLKAQLQQRFTQRLVQLADGAQAIREAGHGPAIVLLHGIGSGAASWLQVALQLSPHARVIAWDAPGYGDS
SPLATPAPQAPDYARRLLQLLDALNIDDCVLVGHSLGALSAAALACQHPQRLRRLVLISPARGYGDPARAEQAQQVRSQR
LHTLEQLGIAQMAQQRGAHMLSPAASAQALGWVQWNMARLQPRGYRQAVELLCGDDLLRYAASTVPCEVHCGAADSITPP
ADCQALAAALGAPFQLIAEAGHASPIEQPEAVASLLARAIEASLTGTAL
Download Length: 870 bp
>T119118 NZ_CP035952:c1814050-1813181 [Pseudomonas sp. SNU WT1]
ATGTCGCACGCCACCGACCACTCGCTCGCAAGCCTCAAGGCCCAGTTGCAACAGCGCTTTACCCAGCGCCTGGTGCAACT
GGCCGACGGCGCCCAGGCGATCCGCGAAGCCGGGCACGGGCCTGCCATCGTGCTGCTGCACGGCATCGGCTCGGGCGCCG
CGTCCTGGCTGCAGGTGGCGTTGCAATTGAGCCCGCACGCCCGGGTGATCGCCTGGGATGCACCGGGCTATGGCGACTCA
AGCCCGCTGGCCACGCCTGCACCGCAAGCCCCTGACTATGCCCGGCGCCTGCTGCAATTGCTCGACGCGCTGAACATCGA
TGACTGCGTGCTGGTCGGCCATTCCCTCGGCGCCCTCAGCGCCGCGGCATTGGCCTGCCAGCATCCGCAACGGCTGCGCC
GCCTGGTGCTGATCAGCCCGGCCCGTGGTTATGGCGACCCAGCGCGCGCCGAGCAGGCACAACAGGTGCGCAGCCAACGC
CTGCACACCCTCGAACAACTGGGCATCGCCCAGATGGCCCAGCAGCGCGGCGCGCACATGCTCTCGCCTGCGGCCAGTGC
CCAGGCCCTGGGCTGGGTGCAATGGAACATGGCGCGCCTGCAGCCCCGGGGTTATCGCCAGGCCGTCGAGCTGCTGTGCG
GTGACGACCTGCTGCGCTACGCCGCAAGCACCGTGCCTTGCGAAGTCCATTGCGGTGCCGCCGACAGCATTACCCCGCCC
GCCGACTGCCAGGCCTTGGCGGCTGCGTTGGGTGCACCGTTCCAGCTGATTGCCGAGGCCGGCCACGCCAGCCCGATCGA
ACAACCCGAGGCCGTGGCAAGCCTGCTTGCCCGGGCCATCGAAGCCTCTCTGACAGGTACTGCGCTATGA
ATGTCGCACGCCACCGACCACTCGCTCGCAAGCCTCAAGGCCCAGTTGCAACAGCGCTTTACCCAGCGCCTGGTGCAACT
GGCCGACGGCGCCCAGGCGATCCGCGAAGCCGGGCACGGGCCTGCCATCGTGCTGCTGCACGGCATCGGCTCGGGCGCCG
CGTCCTGGCTGCAGGTGGCGTTGCAATTGAGCCCGCACGCCCGGGTGATCGCCTGGGATGCACCGGGCTATGGCGACTCA
AGCCCGCTGGCCACGCCTGCACCGCAAGCCCCTGACTATGCCCGGCGCCTGCTGCAATTGCTCGACGCGCTGAACATCGA
TGACTGCGTGCTGGTCGGCCATTCCCTCGGCGCCCTCAGCGCCGCGGCATTGGCCTGCCAGCATCCGCAACGGCTGCGCC
GCCTGGTGCTGATCAGCCCGGCCCGTGGTTATGGCGACCCAGCGCGCGCCGAGCAGGCACAACAGGTGCGCAGCCAACGC
CTGCACACCCTCGAACAACTGGGCATCGCCCAGATGGCCCAGCAGCGCGGCGCGCACATGCTCTCGCCTGCGGCCAGTGC
CCAGGCCCTGGGCTGGGTGCAATGGAACATGGCGCGCCTGCAGCCCCGGGGTTATCGCCAGGCCGTCGAGCTGCTGTGCG
GTGACGACCTGCTGCGCTACGCCGCAAGCACCGTGCCTTGCGAAGTCCATTGCGGTGCCGCCGACAGCATTACCCCGCCC
GCCGACTGCCAGGCCTTGGCGGCTGCGTTGGGTGCACCGTTCCAGCTGATTGCCGAGGCCGGCCACGCCAGCCCGATCGA
ACAACCCGAGGCCGTGGCAAGCCTGCTTGCCCGGGCCATCGAAGCCTCTCTGACAGGTACTGCGCTATGA
Antitoxin
Download Length: 276 a.a. Molecular weight: 30452.85 Da Isoelectric Point: 6.4973
>AT119118 WP_130263619.1 NZ_CP035952:c1813184-1812357 [Pseudomonas sp. SNU WT1]
MNDSDLLKDNQDKYIVPGLERGLLLLCEFSRQNRTLTAPELARRLELPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDHLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSPCTPKTVLELFDLVQSDRQRGYVSGEGFFESSISTIAAPVRDHSGRVVAAMGVTIPSVQVAHINF
DGLLGHVRGSADELSRLLNYTPHAGNGRVTALMRD
MNDSDLLKDNQDKYIVPGLERGLLLLCEFSRQNRTLTAPELARRLELPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDHLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSPCTPKTVLELFDLVQSDRQRGYVSGEGFFESSISTIAAPVRDHSGRVVAAMGVTIPSVQVAHINF
DGLLGHVRGSADELSRLLNYTPHAGNGRVTALMRD
Download Length: 828 bp
>AT119118 NZ_CP035952:c1813184-1812357 [Pseudomonas sp. SNU WT1]
ATGAATGATTCGGATCTGTTGAAAGACAACCAGGACAAGTACATCGTCCCCGGCCTTGAGCGCGGCCTGTTGCTGCTCTG
TGAATTCAGCCGGCAAAACCGCACCCTCACCGCGCCAGAACTGGCGCGGCGCCTGGAGCTGCCGCGCTCGACCATCTTCC
GCCTGCTGACCACCCTGGAAACCATGGGTTTCGTCACCCGCAGCGGCAATGAATACCGCCTGGGCATGTCGGTACTGCGC
CTGGGCTTCGAGTACCTGGCTTCGCTGGAGCTGACCGAACTGGGCCAGCCGCTGCTGGCGCGGCTGTGCGATCACCTGAA
CTACCCGAGCAACCTGGTGGTGCGCGACGGTCGCTCGATCGTTTATGTGGCCAAGGTGTCGCCGCCGTCGGTGTTCTCCA
GCGCGGTCAACGTCGGCACCCGCCTGCCGGCCCACGCCACGGTGCTGGGGCGCATCCTGCTCGAAGACCTGAGCCTGGCC
GAGCTGCGCGAGCTGTACCCCGAGGAGCACCTGGAACAGCACTCGCCGTGCACGCCAAAAACCGTGCTGGAGCTGTTCGA
CCTGGTGCAGAGCGACCGTCAGCGTGGCTACGTCAGCGGCGAAGGCTTCTTCGAGTCGTCGATCTCGACCATCGCCGCCC
CGGTGCGCGATCACAGTGGTCGAGTGGTTGCCGCCATGGGCGTGACCATTCCCTCGGTGCAGGTTGCGCACATCAATTTC
GACGGTCTGCTCGGCCATGTCCGTGGCAGCGCCGACGAGCTGTCGCGCCTGCTCAACTACACCCCGCACGCTGGCAACGG
TCGCGTCACTGCGCTGATGAGGGATTGA
ATGAATGATTCGGATCTGTTGAAAGACAACCAGGACAAGTACATCGTCCCCGGCCTTGAGCGCGGCCTGTTGCTGCTCTG
TGAATTCAGCCGGCAAAACCGCACCCTCACCGCGCCAGAACTGGCGCGGCGCCTGGAGCTGCCGCGCTCGACCATCTTCC
GCCTGCTGACCACCCTGGAAACCATGGGTTTCGTCACCCGCAGCGGCAATGAATACCGCCTGGGCATGTCGGTACTGCGC
CTGGGCTTCGAGTACCTGGCTTCGCTGGAGCTGACCGAACTGGGCCAGCCGCTGCTGGCGCGGCTGTGCGATCACCTGAA
CTACCCGAGCAACCTGGTGGTGCGCGACGGTCGCTCGATCGTTTATGTGGCCAAGGTGTCGCCGCCGTCGGTGTTCTCCA
GCGCGGTCAACGTCGGCACCCGCCTGCCGGCCCACGCCACGGTGCTGGGGCGCATCCTGCTCGAAGACCTGAGCCTGGCC
GAGCTGCGCGAGCTGTACCCCGAGGAGCACCTGGAACAGCACTCGCCGTGCACGCCAAAAACCGTGCTGGAGCTGTTCGA
CCTGGTGCAGAGCGACCGTCAGCGTGGCTACGTCAGCGGCGAAGGCTTCTTCGAGTCGTCGATCTCGACCATCGCCGCCC
CGGTGCGCGATCACAGTGGTCGAGTGGTTGCCGCCATGGGCGTGACCATTCCCTCGGTGCAGGTTGCGCACATCAATTTC
GACGGTCTGCTCGGCCATGTCCGTGGCAGCGCCGACGAGCTGTCGCGCCTGCTCAACTACACCCCGCACGCTGGCAACGG
TCGCGTCACTGCGCTGATGAGGGATTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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