Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 3049318..3049877 Replicon chromosome
Accession NZ_CP035945
Organism Blautia producta strain PMF1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PMF13cell1_RS13455 Protein ID WP_130181033.1
Coordinates 3049593..3049877 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4P6LX53
Locus tag PMF13cell1_RS13450 Protein ID WP_029469812.1
Coordinates 3049318..3049596 (+) Length 93 a.a.

Genomic Context

PMF13cell1_RS13425PMF13cell1_RS13430PMF13cell1_RS13435PMF13cell1_RS13440PMF13cell1_RS13445PMF13cell1_RS13450PMF13cell1_RS13455PMF13cell1_RS13460PMF13cell1_RS13465PMF13cell1_RS13475PMF13cell1_RS13480
Location: 3045398..3046048 (651 bp)
Type: Others
Protein ID: WP_130181029.1
Location: 3046162..3047178 (1017 bp)
Type: Others
Protein ID: WP_130181030.1
Location: 3047276..3047971 (696 bp)
Type: Others
Protein ID: WP_130181031.1
Location: 3047987..3048871 (885 bp)
Type: Others
Protein ID: WP_130181032.1
Location: 3049028..3049165 (138 bp)
Type: Others
Protein ID: WP_029469813.1
Location: 3049318..3049596 (279 bp)
Type: Antitoxin
Protein ID: WP_029469812.1
Location: 3049593..3049877 (285 bp)
Type: Toxin
Protein ID: WP_130181033.1
Location: 3050257..3050853 (597 bp)
Type: Others
Protein ID: WP_130183027.1
Location: 3050904..3051839 (936 bp)
Type: Others
Protein ID: WP_130181034.1
Location: 3051958..3052638 (681 bp)
Type: Others
Protein ID: WP_018593541.1
Location: 3052717..3053739 (1023 bp)
Type: Others
Protein ID: WP_130181035.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PMF13cell1_RS134253045398..3046048+651WP_130181029.1DUF3786 domain-containing protein-
PMF13cell1_RS134303046162..3047178+1017WP_130181030.1nucleotidyltransferase domain-containing protein-
PMF13cell1_RS134353047276..3047971+696WP_130181031.1HD domain-containing protein-
PMF13cell1_RS134403047987..3048871+885WP_130181032.1radical SAM protein-
PMF13cell1_RS134453049028..3049165+138WP_029469813.1helix-turn-helix domain-containing protein-
PMF13cell1_RS134503049318..3049596+279WP_029469812.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
PMF13cell1_RS134553049593..3049877+285WP_130181033.1type II toxin-antitoxin system YafQ family toxinToxin
PMF13cell1_RS134603050257..3050853+597WP_130183027.1isoprenylcysteine carboxylmethyltransferase family protein-
PMF13cell1_RS134653050904..3051839+936WP_130181034.1GNAT family N-acetyltransferase-
PMF13cell1_RS134753051958..3052638+681WP_018593541.1TIGR00266 family protein-
PMF13cell1_RS134803052717..3053739+1023WP_130181035.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-70)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10694.49 Da        Isoelectric Point: 9.5088

>T119115 WP_130181033.1 NZ_CP035945:3049593-3049877 [Blautia producta]
MTKYTVKPTTQFKKDYKLAIKRGLKIELLEEIIISLANGVPLPEKNKDHALGGNWNGHRECHILPDWLLVYRVENDVLVL
TLARAGTHSDLFGK

Download         Length: 285 bp

>T119115 NZ_CP035945:3049593-3049877 [Blautia producta]
ATGACAAAATATACTGTTAAACCTACCACACAATTCAAGAAAGATTACAAGTTAGCAATCAAACGTGGATTGAAAATTGA
GCTATTAGAAGAAATCATCATCAGTCTTGCGAACGGTGTCCCGCTGCCGGAGAAAAACAAAGACCATGCTCTTGGTGGCA
ACTGGAACGGACATCGTGAGTGTCACATCTTACCTGATTGGTTACTTGTATATCGGGTGGAAAATGATGTTCTTGTCTTA
ACGTTGGCTCGCGCAGGCACACACAGCGACTTGTTTGGAAAATAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10179.58 Da        Isoelectric Point: 4.4367

>AT119115 WP_029469812.1 NZ_CP035945:3049318-3049596 [Blautia producta]
MTGNTTNISIRMDAELKSQADELFAELGMNISTAFNIFVRQALREGGIPFDVSLNKPNKETVTAMLEAERIAKDPAVKGY
TDLNQLFADLKE

Download         Length: 279 bp

>AT119115 NZ_CP035945:3049318-3049596 [Blautia producta]
ATGACTGGCAATACAACCAACATCAGCATTCGCATGGATGCGGAACTAAAATCTCAAGCGGATGAGCTTTTTGCAGAGCT
CGGTATGAATATTTCCACGGCGTTTAATATTTTTGTTCGGCAAGCGCTTCGTGAGGGCGGTATTCCTTTTGATGTTTCGC
TGAATAAGCCAAATAAGGAGACCGTTACTGCAATGCTTGAAGCGGAAAGGATTGCGAAAGACCCTGCTGTTAAGGGCTAT
ACTGATCTCAATCAGCTTTTCGCAGATTTGAAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A4P6LX53

References