Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2024780..2025051 Replicon chromosome
Accession NZ_CP035944
Organism Escherichia coli strain AR24.2b

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2024910..2025013 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2024780..2025051 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EXT04_RS09805 2021335..2021997 - 663 WP_000944256.1 exodeoxyribonuclease X -
EXT04_RS09810 2022021..2022677 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EXT04_RS09815 2022779..2023009 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EXT04_RS09820 2023148..2023522 + 375 WP_000204699.1 CopC domain-containing protein YobA -
EXT04_RS09825 2023526..2024398 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
EXT04_RS09830 2024411..2024752 + 342 WP_000976492.1 YebY family protein -
- 2024780..2025051 - 272 - - Antitoxin
- 2024910..2025013 + 104 - - Toxin
EXT04_RS09835 2025148..2025804 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
EXT04_RS09840 2025805..2025996 - 192 WP_001296140.1 YebW family protein -
EXT04_RS09845 2026101..2026337 - 237 WP_001295499.1 DUF1480 family protein -
EXT04_RS09850 2026455..2027894 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T119102 NZ_CP035944:2024910-2025013 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT119102 NZ_CP035944:c2025051-2024780 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References