Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 510848..511481 Replicon chromosome
Accession NZ_CP035934
Organism Acinetobacter cumulans strain WCHAc060092

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag C9E88_RS02420 Protein ID WP_106984051.1
Coordinates 511098..511481 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag C9E88_RS02415 Protein ID WP_106984050.1
Coordinates 510848..511105 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E88_RS02395 506402..506767 + 366 WP_004641032.1 50S ribosomal protein L17 -
C9E88_RS02400 506968..508458 + 1491 WP_106984047.1 NAD(P)/FAD-dependent oxidoreductase -
C9E88_RS02405 508618..509409 + 792 WP_106984048.1 alpha/beta hydrolase -
C9E88_RS02410 509489..510661 - 1173 WP_106984049.1 acyl-CoA dehydrogenase family protein -
C9E88_RS02415 510848..511105 + 258 WP_106984050.1 succinate dehydrogenase assembly factor 2 Antitoxin
C9E88_RS02420 511098..511481 + 384 WP_106984051.1 hypothetical protein Toxin
C9E88_RS02425 512001..513047 + 1047 WP_106984052.1 hypothetical protein -
C9E88_RS02430 513124..513699 + 576 WP_106984053.1 rhombosortase -
C9E88_RS02435 513893..516082 + 2190 WP_106984054.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-125)

Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 15204.32 Da        Isoelectric Point: 10.2694

>T119092 WP_106984051.1 NZ_CP035934:511098-511481 [Acinetobacter cumulans]
MDKRHFQLKPSLIALVFQFAIFAVLMTLLYQVLAIWLWCVFLLLGLVIYALFYRRRPNISALEYLDGRDWTLTKYGQPQR
VQISHIIDHQVYIVVYFQHARTKPMIIWCDQVAFKQWKSLKVLAKMI

Download         Length: 384 bp

>T119092 NZ_CP035934:511098-511481 [Acinetobacter cumulans]
ATGGATAAGCGTCATTTTCAGCTGAAACCTAGTCTGATAGCGCTAGTGTTTCAGTTTGCCATTTTTGCGGTTTTAATGAC
CTTGCTCTATCAGGTTTTAGCCATCTGGCTTTGGTGTGTGTTTCTGCTATTGGGCTTGGTCATCTATGCTTTATTTTATC
GCCGGCGCCCCAATATTAGTGCGCTGGAATATCTGGATGGTCGTGATTGGACCTTGACCAAGTACGGTCAGCCACAGCGT
GTGCAAATCAGTCATATTATTGATCATCAAGTGTATATCGTGGTGTATTTTCAGCATGCACGTACAAAACCAATGATTAT
TTGGTGTGATCAAGTCGCCTTCAAACAGTGGAAGTCATTGAAAGTATTGGCCAAAATGATCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10344.72 Da        Isoelectric Point: 4.4596

>AT119092 WP_106984050.1 NZ_CP035934:510848-511105 [Acinetobacter cumulans]
MTDDISLEERKVIYRARRGLKEIDVYFDPYVKNYYLQADQFEKDMFAELVAQEDPDLLDWFMEVSEPPRPELRDFIQKLK
HYVHG

Download         Length: 258 bp

>AT119092 NZ_CP035934:510848-511105 [Acinetobacter cumulans]
ATGACTGATGACATCAGCTTGGAAGAACGCAAAGTAATTTACCGTGCGCGACGCGGTTTAAAAGAAATTGATGTGTATTT
TGATCCCTACGTAAAAAATTACTACTTGCAAGCAGATCAATTTGAAAAAGACATGTTTGCAGAGTTGGTTGCGCAGGAAG
ATCCAGATTTATTGGATTGGTTTATGGAAGTAAGTGAACCGCCACGCCCAGAATTACGTGATTTTATTCAGAAGTTAAAA
CACTACGTTCATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References