Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 849661..850180 Replicon chromosome
Accession NZ_CP035928
Organism Malaciobacter pacificus strain LMG 26638

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag APAC_RS04375 Protein ID WP_130232960.1
Coordinates 849902..850180 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag APAC_RS04370 Protein ID WP_130232959.1
Coordinates 849661..849912 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APAC_RS04350 845176..846777 + 1602 WP_130232955.1 urea ABC transporter permease subunit UrtB -
APAC_RS04355 846781..847887 + 1107 WP_130232956.1 urea ABC transporter permease subunit UrtC -
APAC_RS04360 847890..848678 + 789 WP_130232957.1 urea ABC transporter ATP-binding protein UrtD -
APAC_RS04365 848682..849377 + 696 WP_130232958.1 urea ABC transporter ATP-binding subunit UrtE -
APAC_RS04370 849661..849912 + 252 WP_130232959.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
APAC_RS04375 849902..850180 + 279 WP_130232960.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
APAC_RS04380 850269..850829 + 561 WP_170170112.1 sel1 repeat family protein -
APAC_RS04385 850996..851745 + 750 WP_130232962.1 urease accessory protein UreD -
APAC_RS04390 851769..852446 + 678 WP_130232963.1 urease subunit beta -
APAC_RS04395 852449..854149 + 1701 WP_130232964.1 urease subunit alpha -
APAC_RS04400 854159..854608 + 450 WP_130232965.1 urease accessory protein UreE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-77)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11017.91 Da        Isoelectric Point: 10.5021

>T119073 WP_130232960.1 NZ_CP035928:849902-850180 [Malaciobacter pacificus]
MSYSLEFNPKALKEWSKLNSTIKEQFKKKLKERLENPRIPKDKLSGFENVYKIKLRNIGYRLAYEVKDEQIVVLVLTVGR
RENNEVYKNLKK

Download         Length: 279 bp

>T119073 NZ_CP035928:849902-850180 [Malaciobacter pacificus]
ATGAGTTATAGTCTAGAGTTTAATCCAAAGGCTTTAAAAGAGTGGTCAAAACTAAATAGTACTATAAAAGAACAATTCAA
AAAGAAACTAAAAGAAAGACTTGAAAATCCAAGAATCCCAAAAGATAAGCTTAGTGGTTTTGAAAATGTCTATAAAATCA
AACTAAGAAATATAGGTTATAGACTAGCTTATGAAGTTAAAGATGAACAAATAGTTGTTTTAGTTCTAACTGTTGGTAGA
AGAGAAAATAACGAAGTCTATAAAAATCTTAAAAAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9401.72 Da        Isoelectric Point: 4.3690

>AT119073 WP_130232959.1 NZ_CP035928:849661-849912 [Malaciobacter pacificus]
MNTILANYTASITELKKSPTELLKNAGDEAIAILNHNSPSAYLIPSKTYEKMMEIIEEYQLSKLVEERLNDSEKSIKVDI
DEL

Download         Length: 252 bp

>AT119073 NZ_CP035928:849661-849912 [Malaciobacter pacificus]
ATGAATACTATATTAGCAAACTATACAGCAAGTATTACAGAACTTAAAAAATCTCCAACTGAATTATTAAAAAATGCAGG
AGATGAAGCAATAGCTATTTTAAATCATAATAGCCCAAGTGCATACTTAATTCCATCAAAAACTTATGAAAAAATGATGG
AAATAATAGAAGAATATCAATTATCTAAATTAGTAGAAGAAAGATTAAATGATAGTGAAAAATCTATCAAAGTAGATATT
GATGAGTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References