Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1202002..1202511 Replicon chromosome
Accession NZ_CP035926
Organism Arcobacter thereius LMG 24486

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ATH_RS06210 Protein ID WP_066390238.1
Coordinates 1202002..1202274 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ATH_RS06215 Protein ID WP_066390237.1
Coordinates 1202278..1202511 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ATH_RS06185 1197695..1198846 + 1152 WP_066390251.1 ATP-binding protein -
ATH_RS06190 1199119..1199931 + 813 WP_066390250.1 hypothetical protein -
ATH_RS06195 1200144..1200461 + 318 WP_066390244.1 hypothetical protein -
ATH_RS06200 1200473..1201123 + 651 WP_066390243.1 hypothetical protein -
ATH_RS06205 1201768..1201953 + 186 WP_066390240.1 hypothetical protein -
ATH_RS06210 1202002..1202274 - 273 WP_066390238.1 type II toxin-antitoxin system YafQ family toxin Toxin
ATH_RS06215 1202278..1202511 - 234 WP_066390237.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
ATH_RS06220 1202579..1203664 - 1086 WP_066390235.1 site-specific integrase -
ATH_RS06230 1204374..1204640 + 267 WP_066184591.1 hypothetical protein -
ATH_RS06235 1204845..1205927 + 1083 WP_066184593.1 tyrosine-type recombinase/integrase -
ATH_RS09885 1205973..1206113 - 141 WP_165595846.1 hypothetical protein -
ATH_RS06240 1206182..1206400 - 219 WP_066184594.1 cold-shock protein -
ATH_RS06245 1206688..1207050 - 363 WP_066184597.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-71)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10676.44 Da        Isoelectric Point: 9.2522

>T119071 WP_066390238.1 NZ_CP035926:c1202274-1202002 [Arcobacter thereius LMG 24486]
MYKLFRTKQFIKDYGKTKLSDKHYEKYIKFVSLLLENKKLPSEALDHELVGNYLGFRECHISGDMLLIYIIEDGYLKLTR
IGTHNQLFNS

Download         Length: 273 bp

>T119071 NZ_CP035926:c1202274-1202002 [Arcobacter thereius LMG 24486]
ATGTATAAACTATTTAGAACAAAACAGTTTATAAAAGATTATGGTAAAACAAAGCTGTCTGATAAACACTATGAAAAATA
TATAAAGTTTGTTAGTTTATTATTGGAAAATAAGAAACTACCATCAGAAGCTTTAGATCATGAACTTGTTGGAAATTATC
TTGGCTTTAGAGAGTGTCATATTAGTGGTGATATGCTTTTAATTTATATAATAGAAGATGGTTATTTAAAATTAACAAGA
ATAGGTACACATAATCAATTATTTAATAGCTAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8688.19 Da        Isoelectric Point: 6.3216

>AT119071 WP_066390237.1 NZ_CP035926:c1202511-1202278 [Arcobacter thereius LMG 24486]
MMDSTVRARVDSDLKQEAEAIFKKLGLSTSQAIVMFLNMVKLNNGIPFEVKIPNKDTLKAMQEAKEFKGEEITLKDL

Download         Length: 234 bp

>AT119071 NZ_CP035926:c1202511-1202278 [Arcobacter thereius LMG 24486]
ATGATGGATTCAACAGTTAGAGCTAGAGTTGATAGTGATTTAAAACAAGAAGCAGAAGCTATTTTTAAAAAGTTAGGACT
TAGTACATCTCAAGCAATAGTGATGTTTTTAAATATGGTAAAACTTAATAATGGTATTCCATTTGAGGTAAAAATTCCAA
ATAAAGATACTCTAAAAGCTATGCAAGAAGCTAAAGAGTTTAAGGGTGAAGAAATCACTTTAAAAGATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References