Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 319730..320433 Replicon chromosome
Accession NZ_CP035914
Organism Synechococcus sp. WH 8101

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SynWH8101_RS01435 Protein ID WP_130128276.1
Coordinates 319730..320170 (-) Length 147 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SynWH8101_RS01440 Protein ID WP_130128277.1
Coordinates 320167..320433 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynWH8101_RS01410 315691..316908 - 1218 WP_130130288.1 DegT/DnrJ/EryC1/StrS family aminotransferase -
SynWH8101_RS01415 316981..317532 + 552 WP_165380897.1 hypothetical protein -
SynWH8101_RS01420 317513..317956 - 444 WP_130128273.1 hypothetical protein -
SynWH8101_RS01425 317956..318834 - 879 WP_130128274.1 deoxyribodipyrimidine photo-lyase -
SynWH8101_RS01430 318911..319693 + 783 WP_130128275.1 enoyl-ACP reductase FabI -
SynWH8101_RS01435 319730..320170 - 441 WP_130128276.1 PIN domain-containing protein Toxin
SynWH8101_RS01440 320167..320433 - 267 WP_130128277.1 DUF2191 domain-containing protein Antitoxin
SynWH8101_RS01445 320559..321164 + 606 WP_130130290.1 imidazoleglycerol-phosphate dehydratase HisB -
SynWH8101_RS01450 321241..322773 + 1533 WP_130128278.1 carotenoid oxygenase family protein -
SynWH8101_RS01455 322727..323638 - 912 WP_130128279.1 hypothetical protein -
SynWH8101_RS01460 323778..324506 + 729 WP_165380898.1 SIMPL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-134)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 16368.84 Da        Isoelectric Point: 6.6853

>T119062 WP_130128276.1 NZ_CP035914:c320170-319730 [Synechococcus sp. WH 8101]
VILIDTNLWLYASLRETPHHSAAKAWLEATLNGDEAIALPWSVVLAVLCISTQHRLMLHPLKPEQALDLVEGWLQHPLVE
VLQPSRTHWDRLRLLLQDAGTAGNRTSDAHLAALAIEHNCLLCSADSDFRRFAGLRFCNPLRAAER

Download         Length: 441 bp

>T119062 NZ_CP035914:c320170-319730 [Synechococcus sp. WH 8101]
GTGATTCTGATCGACACCAACCTCTGGCTCTACGCGTCGCTGAGGGAGACTCCTCATCACAGCGCCGCGAAGGCCTGGCT
GGAAGCCACGCTCAATGGCGACGAAGCCATCGCTCTGCCCTGGAGCGTGGTGTTAGCCGTCCTGTGCATCAGCACCCAGC
ATCGCTTGATGTTGCACCCCCTCAAGCCTGAGCAAGCCCTGGATCTGGTGGAAGGCTGGCTGCAGCATCCCCTGGTAGAG
GTGCTGCAGCCGTCCCGGACACACTGGGATCGACTGCGCCTGCTGCTTCAGGACGCTGGCACGGCGGGCAATCGCACCAG
TGATGCGCACCTGGCTGCGCTGGCGATCGAGCACAACTGCCTGCTCTGCTCGGCTGACAGCGATTTTCGCCGCTTCGCGG
GCCTGCGCTTCTGTAATCCACTGCGTGCAGCGGAGCGATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9684.12 Da        Isoelectric Point: 10.3533

>AT119062 WP_130128277.1 NZ_CP035914:c320433-320167 [Synechococcus sp. WH 8101]
MRTTLSIDDVLLRQLRQKALDSGKPFKQVVNDTLRAGLHQAASPQRQPYRCPTFSIGALAPGVDLSKANQLAAGLEDEAL
LEKLRQSR

Download         Length: 267 bp

>AT119062 NZ_CP035914:c320433-320167 [Synechococcus sp. WH 8101]
ATGCGAACCACGCTCAGTATCGACGACGTTCTGCTCCGGCAGCTGCGTCAGAAGGCGCTCGACAGCGGCAAGCCGTTCAA
GCAAGTGGTGAATGACACGCTGCGGGCGGGCCTCCATCAGGCCGCCTCACCCCAGCGCCAGCCCTACCGCTGCCCGACGT
TTTCGATCGGAGCCCTGGCACCGGGTGTGGATCTCAGCAAAGCCAATCAGCTGGCCGCTGGCCTCGAAGATGAAGCGCTG
CTCGAGAAGCTGCGCCAAAGCCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References