Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 493917..494188 Replicon chromosome
Accession NZ_CP035870
Organism Escherichia coli strain E2528-C1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 494047..494150 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 493917..494188 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW999_RS02520 490472..491134 - 663 WP_000944258.1 exodeoxyribonuclease X -
EW999_RS02525 491158..491814 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
EW999_RS02530 491916..492146 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EW999_RS02535 492285..492659 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EW999_RS02540 492663..493535 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
EW999_RS02545 493548..493889 + 342 WP_000976472.1 YebY family protein -
- 493917..494188 - 272 - - Antitoxin
- 494047..494150 + 104 - - Toxin
EW999_RS02550 494285..494941 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
EW999_RS02555 494942..495133 - 192 WP_001338167.1 YebW family protein -
EW999_RS02560 495238..495474 - 237 WP_001338166.1 YebV family protein -
EW999_RS02565 495592..497031 - 1440 WP_001397399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 425308..510026 84718


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T118910 NZ_CP035870:494047-494150 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT118910 NZ_CP035870:c494188-493917 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References