Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3429691..3429962 Replicon chromosome
Accession NZ_CP035850
Organism Escherichia coli strain TW10590

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3429821..3429924 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3429691..3429962 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EXE32_RS16480 3426246..3426908 - 663 WP_000944256.1 exodeoxyribonuclease X -
EXE32_RS16485 3426932..3427588 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
EXE32_RS16490 3427690..3427920 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EXE32_RS16495 3428059..3428433 + 375 WP_000204699.1 CopC domain-containing protein YobA -
EXE32_RS16500 3428437..3429309 + 873 WP_000879279.1 copper homeostasis membrane protein CopD -
EXE32_RS16505 3429322..3429663 + 342 WP_000976492.1 YebY family protein -
- 3429691..3429962 - 272 - - Antitoxin
- 3429821..3429924 + 104 - - Toxin
EXE32_RS16510 3430059..3430715 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
EXE32_RS16515 3430716..3430907 - 192 WP_001296140.1 YebW family protein -
EXE32_RS16520 3431012..3431248 - 237 WP_001295499.1 YebV family protein -
EXE32_RS16525 3431366..3432805 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T118804 NZ_CP035850:3429821-3429924 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT118804 NZ_CP035850:c3429962-3429691 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References