Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4803263..4803534 Replicon chromosome
Accession NZ_CP035846
Organism Escherichia coli strain TW10598

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4803393..4803496 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4803263..4803534 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EXA01_RS23355 4799818..4800480 - 663 WP_000944258.1 exodeoxyribonuclease X -
EXA01_RS23360 4800504..4801160 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
EXA01_RS23365 4801262..4801492 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EXA01_RS23370 4801631..4802005 + 375 WP_000168746.1 CopC domain-containing protein YobA -
EXA01_RS23375 4802009..4802881 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
EXA01_RS23380 4802894..4803235 + 342 WP_000976472.1 YebY family protein -
- 4803263..4803534 - 272 - - Antitoxin
- 4803393..4803496 + 104 - - Toxin
EXA01_RS23385 4803631..4804287 + 657 WP_000812772.1 protein-serine/threonine phosphatase -
EXA01_RS23390 4804288..4804479 - 192 WP_001338167.1 YebW family protein -
EXA01_RS23395 4804584..4804820 - 237 WP_001338166.1 YebV family protein -
EXA01_RS23400 4804938..4806377 - 1440 WP_001397399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T118779 NZ_CP035846:4803393-4803496 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT118779 NZ_CP035846:c4803534-4803263 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References