Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4606018..4606289 Replicon chromosome
Accession NZ_CP035841
Organism Escherichia coli strain TW10722

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4606148..4606251 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4606018..4606289 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EXA02_RS22555 4602573..4603235 - 663 WP_000944256.1 exodeoxyribonuclease X -
EXA02_RS22560 4603259..4603915 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
EXA02_RS22565 4604017..4604247 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EXA02_RS22570 4604386..4604760 + 375 WP_000204699.1 CopC domain-containing protein YobA -
EXA02_RS22575 4604764..4605636 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
EXA02_RS22580 4605649..4605990 + 342 WP_000976472.1 YebY family protein -
- 4606018..4606289 - 272 - - Antitoxin
- 4606148..4606251 + 104 - - Toxin
EXA02_RS22585 4606386..4607042 + 657 WP_000812735.1 protein-serine/threonine phosphatase -
EXA02_RS22590 4607043..4607234 - 192 WP_001296140.1 YebW family protein -
EXA02_RS22595 4607339..4607575 - 237 WP_001295499.1 YebV family protein -
EXA02_RS22600 4607693..4609132 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T118749 NZ_CP035841:4606148-4606251 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT118749 NZ_CP035841:c4606289-4606018 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References