Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4918096..4918367 Replicon chromosome
Accession NZ_CP035826
Organism Escherichia coli strain 67-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4918134..4918237 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4918096..4918367 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EXA05_RS23975 4915253..4916692 + 1440 WP_001383086.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EXA05_RS23980 4916810..4917046 + 237 WP_001295499.1 YebV family protein -
EXA05_RS23985 4917151..4917342 + 192 WP_001313035.1 YebW family protein -
EXA05_RS23990 4917343..4917999 - 657 WP_000812739.1 protein-serine/threonine phosphatase -
- 4918096..4918367 + 272 - - Antitoxin
- 4918134..4918237 - 104 - - Toxin
EXA05_RS23995 4918395..4918736 - 342 WP_000976472.1 YebY family protein -
EXA05_RS24000 4918749..4919621 - 873 WP_000879298.1 copper homeostasis membrane protein CopD -
EXA05_RS24005 4919625..4919999 - 375 WP_000168736.1 CopC domain-containing protein YobA -
EXA05_RS24010 4920138..4920368 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EXA05_RS24015 4920470..4921126 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
EXA05_RS24020 4921150..4921812 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T118660 NZ_CP035826:c4918237-4918134 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT118660 NZ_CP035826:4918096-4918367 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References