Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 170096..170620 Replicon chromosome
Accession NZ_CP035810
Organism Brevibacterium luteolum strain NEB1784

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EW640_RS00740 Protein ID WP_165882541.1
Coordinates 170096..170350 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EW640_RS00745 Protein ID WP_165882542.1
Coordinates 170351..170620 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW640_RS00715 165288..165542 + 255 WP_165882536.1 hypothetical protein -
EW640_RS00720 165552..166448 + 897 WP_165882537.1 bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase -
EW640_RS00725 166610..168268 + 1659 WP_165882538.1 AMP-binding protein -
EW640_RS00730 168303..169718 + 1416 WP_165882539.1 TIGR00366 family protein -
EW640_RS00735 169850..170071 + 222 WP_165882540.1 hypothetical protein -
EW640_RS00740 170096..170350 - 255 WP_165882541.1 Txe/YoeB family addiction module toxin Toxin
EW640_RS00745 170351..170620 - 270 WP_165882542.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EW640_RS00750 170852..174433 + 3582 WP_165882543.1 chromosome segregation protein SMC -
EW640_RS00755 174585..174977 + 393 WP_102162565.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-67)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10010.42 Da        Isoelectric Point: 8.8385

>T118540 WP_165882541.1 NZ_CP035810:c170350-170096 [Brevibacterium luteolum]
VRLVWDRSAWEDYKYWQATDRKILKRVNTLIDACLREPFAGIGKPEQLKYGAQGAWSRRITEEHRLVYLVDGDDVVILQA
RYHY

Download         Length: 255 bp

>T118540 NZ_CP035810:c170350-170096 [Brevibacterium luteolum]
GTGCGGTTGGTCTGGGACCGGTCAGCCTGGGAGGACTACAAGTACTGGCAGGCTACTGACCGGAAGATACTTAAGCGCGT
CAATACGCTCATCGATGCATGCTTGCGCGAGCCCTTCGCCGGCATCGGCAAGCCGGAGCAGCTCAAGTACGGTGCGCAAG
GGGCCTGGTCGCGTCGGATCACTGAGGAGCACAGGCTCGTCTATCTTGTCGACGGTGACGACGTGGTGATCCTGCAGGCT
CGCTACCATTACTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10075.11 Da        Isoelectric Point: 4.4453

>AT118540 WP_165882542.1 NZ_CP035810:c170620-170351 [Brevibacterium luteolum]
MSISASEARKTLFPLIERINDDREAVEIVSRKGNAVLMPADEYAAWQETAYLFRSPANARRLLDAYERATSGSTELHELD
RTDEADRSD

Download         Length: 270 bp

>AT118540 NZ_CP035810:c170620-170351 [Brevibacterium luteolum]
ATGTCCATCAGCGCCAGCGAGGCCCGTAAGACCCTGTTCCCCCTCATCGAACGCATCAACGATGATCGGGAGGCCGTCGA
GATCGTCTCCCGGAAGGGCAACGCCGTCCTCATGCCGGCCGACGAGTATGCGGCATGGCAGGAGACTGCCTACCTGTTCC
GCTCACCGGCCAATGCCCGTCGGCTGCTCGACGCGTACGAGCGCGCCACCTCGGGCAGCACCGAGCTGCACGAACTCGAC
CGCACCGACGAGGCAGATAGGTCCGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References