Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2950003..2950652 Replicon chromosome
Accession NZ_CP035806
Organism Leucobacter triazinivorans strain JW-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EVS81_RS13385 Protein ID WP_130110804.1
Coordinates 2950003..2950422 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EVS81_RS13390 Protein ID WP_130110805.1
Coordinates 2950419..2950652 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EVS81_RS13360 2945839..2946303 + 465 WP_130110801.1 single-stranded DNA-binding protein -
EVS81_RS13365 2946313..2946918 + 606 WP_130110802.1 hypothetical protein -
EVS81_RS13370 2947033..2948514 - 1482 WP_165384271.1 recombinase family protein -
EVS81_RS13375 2948598..2949095 + 498 Protein_2617 ABC transporter ATP-binding protein -
EVS81_RS13380 2949163..2949868 + 706 Protein_2618 transposase -
EVS81_RS13385 2950003..2950422 - 420 WP_130110804.1 type II toxin-antitoxin system VapC family toxin Toxin
EVS81_RS13390 2950419..2950652 - 234 WP_130110805.1 toxin-antitoxin system Antitoxin
EVS81_RS13395 2950748..2951470 - 723 WP_165384272.1 zinc ribbon domain-containing protein -
EVS81_RS13400 2951427..2951603 - 177 WP_130110807.1 recombinase family protein -
EVS81_RS13410 2952604..2954103 + 1500 WP_130110808.1 arylsulfatase -
EVS81_RS13415 2954100..2955035 + 936 WP_130110809.1 formylglycine-generating enzyme family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15107.25 Da        Isoelectric Point: 5.7210

>T118531 WP_130110804.1 NZ_CP035806:c2950422-2950003 [Leucobacter triazinivorans]
VIVLDTNVISEVFKPQPNPQVVAWLESLTGDVAITTITLAELLAGVRRRPDGRRKSVLMTSINTAMQSYRDTSAVLGFDD
AAAEHYADIVVARERSGLPITMADAQIAAICRSHRASCATRNTKDFAETGVELLNPWVP

Download         Length: 420 bp

>T118531 NZ_CP035806:c2950422-2950003 [Leucobacter triazinivorans]
GTGATCGTTCTCGACACGAACGTGATCTCGGAGGTGTTCAAGCCGCAACCGAACCCCCAGGTCGTTGCCTGGCTCGAATC
ACTCACCGGAGACGTGGCTATCACGACGATCACGCTCGCCGAGCTCCTCGCCGGTGTTCGCCGACGGCCAGACGGCCGCC
GCAAATCGGTACTCATGACGAGCATCAACACGGCGATGCAGTCGTATCGAGATACGAGCGCGGTTCTGGGGTTCGATGAT
GCTGCCGCCGAGCACTATGCAGATATCGTGGTAGCCCGAGAACGATCCGGCCTTCCGATCACGATGGCCGATGCCCAGAT
CGCAGCGATCTGCCGTAGCCACCGGGCAAGCTGCGCAACCCGCAACACAAAGGACTTCGCTGAGACCGGGGTCGAACTCC
TCAATCCGTGGGTGCCCTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8539.79 Da        Isoelectric Point: 6.4643

>AT118531 WP_130110805.1 NZ_CP035806:c2950652-2950419 [Leucobacter triazinivorans]
MTSIMVRGLDESVKQRLTQQAKEHGRSMEAEVRDILTRAARRPHVGLALMQAAQDVGGIDELQIPARTDAARMVDLE

Download         Length: 234 bp

>AT118531 NZ_CP035806:c2950652-2950419 [Leucobacter triazinivorans]
ATGACATCGATTATGGTTCGCGGGCTCGATGAGTCGGTCAAGCAGCGCCTGACGCAGCAGGCAAAGGAGCACGGCCGCTC
CATGGAGGCGGAGGTTCGTGACATTCTGACTCGGGCCGCTCGTCGCCCTCATGTCGGGCTGGCACTCATGCAGGCAGCCC
AAGATGTGGGCGGGATTGATGAGTTGCAGATTCCGGCACGCACCGACGCGGCACGGATGGTGGATCTCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References