Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2916461..2916729 Replicon chromosome
Accession NZ_CP035772
Organism Escherichia coli O145 strain RM8843-C1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2916499..2916602 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2916461..2916729 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW648_RS14545 2913618..2915057 + 1440 WP_024221588.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EW648_RS14550 2915175..2915411 + 237 WP_001295499.1 DUF1480 family protein -
EW648_RS14555 2915516..2915707 + 192 WP_001313035.1 YebW family protein -
EW648_RS14560 2915708..2916364 - 657 WP_000812714.1 protein-serine/threonine phosphatase -
- 2916461..2916729 + 269 - - Antitoxin
- 2916499..2916602 - 104 - - Toxin
EW648_RS14565 2916759..2917100 - 342 WP_000976475.1 YebY family protein -
EW648_RS14570 2917113..2917985 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
EW648_RS14575 2917989..2918363 - 375 WP_000168738.1 CopC domain-containing protein YobA -
EW648_RS14580 2918502..2918732 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EW648_RS14585 2918834..2919490 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
EW648_RS14590 2919514..2920176 + 663 WP_000944252.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T118490 NZ_CP035772:c2916602-2916499 [Escherichia coli O145]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT118490 NZ_CP035772:2916461-2916729 [Escherichia coli O145]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References