Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2338754..2339022 Replicon chromosome
Accession NZ_CP035767
Organism Escherichia coli O145 strain RM12522-C8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2338792..2338895 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2338754..2339022 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW647_RS12075 2335911..2337350 + 1440 WP_024221588.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EW647_RS12080 2337468..2337704 + 237 WP_001295499.1 DUF1480 family protein -
EW647_RS12085 2337809..2338000 + 192 WP_001313035.1 YebW family protein -
EW647_RS12090 2338001..2338657 - 657 WP_000812714.1 protein-serine/threonine phosphatase -
- 2338754..2339022 + 269 - - Antitoxin
- 2338792..2338895 - 104 - - Toxin
EW647_RS12095 2339052..2339393 - 342 WP_000976475.1 YebY family protein -
EW647_RS12100 2339406..2340278 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
EW647_RS12105 2340282..2340656 - 375 WP_000168738.1 CopC domain-containing protein YobA -
EW647_RS12110 2340795..2341025 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EW647_RS12115 2341127..2341783 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
EW647_RS12120 2341807..2342469 + 663 WP_000944252.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T118410 NZ_CP035767:c2338895-2338792 [Escherichia coli O145]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT118410 NZ_CP035767:2338754-2339022 [Escherichia coli O145]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References