Detailed information of TA system TA118295

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/PRK09907-MazE
• Location: 3259237..3259817
• Replicon: chromosome
• Accession: NZ_CP035704
• Organism: Pseudolysobacter antarcticus strain AQ6-296

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: ELE36_RS13965
• Protein ID: WP_129834304.1
• Coordinates: 3259237..3259575 (-)
• Length: 113 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: -
• Locus tag: ELE36_RS13970
• Protein ID: WP_129834306.1
• Coordinates: 3259575..3259817 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELE36_RS13940	3254749..3255288	+	540	WP_129834294.1	hypothetical protein	-
ELE36_RS13945	3255363..3256739	+	1377	WP_129834296.1	hypothetical protein	-
ELE36_RS13950	3256928..3257614	+	687	WP_207215950.1	glycosyltransferase	-
ELE36_RS13955	3257611..3258021	+	411	WP_129834300.1	DUF2304 domain-containing protein	-
ELE36_RS13960	3258037..3259188	+	1152	WP_129834302.1	glycosyltransferase	-
ELE36_RS13965	3259237..3259575	-	339	WP_129834304.1	endoribonuclease MazF	Toxin
ELE36_RS13970	3259575..3259817	-	243	WP_129834306.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
ELE36_RS13975	3259930..3261345	-	1416	WP_129834308.1	hypothetical protein	-
ELE36_RS13980	3261418..3262629	-	1212	WP_129834310.1	hypothetical protein	-
ELE36_RS13985	3262626..3263528	-	903	WP_129836888.1	ferritin-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (9-105)

Antitoxin

• Antitoxin PemI-like (1-79)

Sequences

Toxin

Protein

• Length: 113 a.a.
• Molecular weight: 12271.32 Da
• Isoelectric Point: 9.8314

>T118295 WP_129834304.1 NZ_CP035704:c3259575-3259237 [Pseudolysobacter antarcticus]
MARRYVPDAGDIVWLHFDPQAGHEQAGHRPALVLSPSLYNSKTGLMLCCPMTTQVKAYPFEVLIAGTRLGVALADQVKSL
DWVVRRASYKGKVSTAELAEVRAKIFSLLGKS

Nucleotide

• Length: 339 bp

>T118295 NZ_CP035704:c3259575-3259237 [Pseudolysobacter antarcticus]
ATGGCTCGCCGTTACGTGCCTGACGCGGGCGATATCGTATGGCTGCATTTTGATCCGCAAGCCGGCCATGAGCAGGCGGG
GCACAGACCGGCACTGGTGCTTAGCCCGTCGCTCTACAACAGCAAAACGGGGCTGATGCTCTGCTGCCCAATGACCACGC
AGGTGAAAGCTTATCCATTTGAAGTATTGATTGCAGGTACGCGTTTGGGCGTGGCATTGGCCGACCAGGTTAAAAGTCTG
GATTGGGTTGTACGCAGGGCCAGCTATAAAGGCAAAGTTTCGACTGCCGAATTGGCAGAAGTTCGGGCGAAGATATTTTC
CTTGCTCGGGAAATCGTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8621.78 Da
• Isoelectric Point: 4.1074

>AT118295 WP_129834306.1 NZ_CP035704:c3259817-3259575 [Pseudolysobacter antarcticus]
MRVLVKKWGNSASVRIPAAIMDAASLSLDDVVDVREEGGSIVIEPVRPSEFDLAQLLADITPENLHTEISFGNAVGNEVF

Nucleotide

• Length: 243 bp

>AT118295 NZ_CP035704:c3259817-3259575 [Pseudolysobacter antarcticus]
ATGCGCGTGCTGGTAAAAAAGTGGGGGAATAGCGCATCAGTCCGCATTCCTGCCGCCATTATGGATGCAGCAAGCTTGAG
CCTGGACGATGTCGTGGATGTTCGCGAGGAAGGCGGCAGCATTGTCATTGAGCCGGTACGCCCGAGCGAATTTGATCTTG
CTCAACTGCTGGCTGATATCACCCCGGAGAACCTGCATACCGAGATCAGTTTCGGCAACGCCGTCGGTAATGAAGTATTT
TGA