Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 1059669..1060289 Replicon chromosome
Accession NZ_CP035704
Organism Pseudolysobacter antarcticus strain AQ6-296

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ELE36_RS04560 Protein ID WP_129831962.1
Coordinates 1059669..1059956 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag ELE36_RS04565 Protein ID WP_129831963.1
Coordinates 1059969..1060289 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELE36_RS04540 1055895..1057265 + 1371 WP_129831958.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
ELE36_RS04545 1057413..1058099 + 687 WP_129831959.1 cytochrome b/b6 domain-containing protein -
ELE36_RS04550 1058187..1058645 - 459 WP_129831960.1 cytochrome c -
ELE36_RS04555 1058783..1059565 + 783 WP_129831961.1 dienelactone hydrolase family protein -
ELE36_RS04560 1059669..1059956 + 288 WP_129831962.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ELE36_RS04565 1059969..1060289 + 321 WP_129831963.1 putative addiction module antidote protein Antitoxin
ELE36_RS04570 1060341..1061270 - 930 WP_129836614.1 polyprenyl synthetase family protein -
ELE36_RS04575 1061442..1062452 - 1011 WP_129831964.1 dipeptide epimerase -
ELE36_RS04580 1062449..1063480 - 1032 WP_129831965.1 DUF1611 domain-containing protein -
ELE36_RS04585 1063758..1065284 + 1527 WP_207215859.1 amidohydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-95)

Antitoxin

Uncharacterized protein HI1420

(8-104)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10749.34 Da        Isoelectric Point: 10.3105

>T118293 WP_129831962.1 NZ_CP035704:1059669-1059956 [Pseudolysobacter antarcticus]
MRVQTTEVYRNWINALKDRIGRARIQMRVDRLAHGNPGQHRNLTDGVSELKIDIGPGYRVYYTEKNGELIVLLAGGDKSS
QQQDIKIAMALAKNL

Download         Length: 288 bp

>T118293 NZ_CP035704:1059669-1059956 [Pseudolysobacter antarcticus]
ATGCGAGTGCAGACAACAGAAGTCTACCGAAATTGGATCAACGCGCTGAAAGATCGCATCGGTCGTGCTCGAATTCAGAT
GCGTGTGGATCGGCTGGCTCACGGTAATCCTGGGCAACATCGCAACCTCACGGACGGTGTCTCCGAATTGAAAATCGATA
TTGGCCCGGGTTATCGCGTCTACTACACCGAGAAAAATGGCGAGCTTATCGTCCTCCTTGCTGGCGGTGATAAATCGAGT
CAGCAGCAAGACATAAAGATCGCCATGGCACTCGCGAAAAACCTTTAG

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11242.93 Da        Isoelectric Point: 9.5098

>AT118293 WP_129831963.1 NZ_CP035704:1059969-1060289 [Pseudolysobacter antarcticus]
MLKVTSKKIAKTKTVAYDVAEQLRTPEEMAAYLDAWLTDAPDDAAGIARALGDIARAKGMSQVARDAGLSRESLYKALGE
NGNPSFATVLKVARALGLRLHADAAI

Download         Length: 321 bp

>AT118293 NZ_CP035704:1059969-1060289 [Pseudolysobacter antarcticus]
ATGCTCAAGGTAACTTCAAAAAAAATTGCCAAGACCAAGACTGTGGCCTACGACGTGGCCGAACAGTTGCGTACGCCAGA
GGAAATGGCCGCTTATCTCGATGCGTGGTTGACCGACGCGCCTGATGATGCGGCGGGCATCGCGCGCGCACTCGGTGACA
TCGCGCGTGCGAAGGGCATGTCGCAGGTTGCGCGTGATGCGGGCCTCAGTCGCGAGAGTCTTTACAAAGCGCTTGGCGAG
AACGGCAATCCGAGTTTTGCGACCGTGCTCAAAGTCGCTCGTGCACTTGGCTTGCGTCTGCATGCAGATGCGGCGATTTA
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References