Detailed information of TA system TA118291

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasABC/RelE-HTH
• Location: 13274..13754
• Replicon: plasmid unnamed1
• Accession: NZ_CP035703
• Organism: Pseudolysobacter antarcticus strain AQ6-296

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: -
• Locus tag: ELE36_RS00090
• Protein ID: WP_129831152.1
• Coordinates: 13482..13754 (+)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: ELE36_RS00085
• Protein ID: WP_129831151.1
• Coordinates: 13274..13498 (+)
• Length: 75 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELE36_RS00065	8723..9073	-	351	WP_129831147.1	hypothetical protein	-
ELE36_RS00070	11234..12169	-	936	WP_129831148.1	replication initiator protein A	-
ELE36_RS00075	12226..12453	-	228	WP_129831149.1	hypothetical protein	-
ELE36_RS00080	12484..13107	-	624	WP_129831150.1	ParA family protein	-
ELE36_RS00085	13274..13498	+	225	WP_129831151.1	TraY domain-containing protein	Antitoxin
ELE36_RS00090	13482..13754	+	273	WP_129831152.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ELE36_RS00095	13941..14570	-	630	WP_129831153.1	hypothetical protein	-
ELE36_RS00100	14640..15269	-	630	WP_129831154.1	hypothetical protein	-
ELE36_RS00105	15589..16533	-	945	WP_129831155.1	tyrosine-type recombinase/integrase	-
ELE36_RS00110	16537..16806	-	270	WP_129831156.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..17196	17196

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-88)

Antitoxin

• Protein of unknown function DUF6290 (3-69)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10567.32 Da
• Isoelectric Point: 10.3355

>T118291 WP_129831152.1 NZ_CP035703:13482-13754 [Pseudolysobacter antarcticus]
MAWRIRFDPAAQKELSKLGHESAKRILKFLHERVVKLDDPRSIGEALKGSELGEFWKYRVGDYRIIADIQDNVLCILVVR
VGNRREVYRK

Nucleotide

• Length: 273 bp

>T118291 NZ_CP035703:13482-13754 [Pseudolysobacter antarcticus]
ATGGCGTGGCGGATTAGATTCGATCCAGCGGCGCAAAAAGAGCTCTCCAAGCTCGGTCACGAATCGGCCAAACGCATCCT
GAAATTCCTGCATGAGCGCGTCGTCAAACTGGACGATCCTCGCAGTATCGGCGAGGCGCTAAAAGGCTCGGAACTCGGCG
AATTCTGGAAATATCGCGTGGGTGATTACCGCATCATCGCGGACATTCAGGATAACGTGCTGTGCATCTTGGTTGTGCGT
GTTGGCAATCGACGCGAGGTATATCGAAAGTAA

Antitoxin

Protein

• Length: 75 a.a.
• Molecular weight: 8431.67 Da
• Isoelectric Point: 4.4678

>AT118291 WP_129831151.1 NZ_CP035703:13274-13498 [Pseudolysobacter antarcticus]
MLAIRLPTEIEDRLDALAKATGRTKTFYAREAILEHIDDLEDLYLAEQRLIEIRAGRTATIPLEDVMKQYGVAD

Nucleotide

• Length: 225 bp

>AT118291 NZ_CP035703:13274-13498 [Pseudolysobacter antarcticus]
ATGCTTGCTATCCGCCTTCCCACTGAAATCGAAGATCGTCTGGATGCGCTGGCGAAGGCAACAGGGCGCACAAAAACCTT
CTACGCCCGCGAAGCCATCCTTGAACACATTGATGACCTGGAAGACCTCTATCTGGCCGAGCAACGCCTGATTGAGATTC
GTGCCGGGCGCACCGCAACCATTCCACTCGAAGACGTGATGAAACAGTATGGCGTGGCGGATTAG