Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-RelB |
| Location | 148536..149095 | Replicon | chromosome |
| Accession | NZ_CP035700 | ||
| Organism | Vibrio alginolyticus strain 2013V-1302 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A347UR22 |
| Locus tag | EPB57_RS08890 | Protein ID | WP_005398411.1 |
| Coordinates | 148536..148814 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A347UR21 |
| Locus tag | EPB57_RS08895 | Protein ID | WP_005398409.1 |
| Coordinates | 148811..149095 (-) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EPB57_RS08870 | 144592..145749 | + | 1158 | WP_154204499.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| EPB57_RS08875 | 147297..147773 | + | 477 | WP_017191310.1 | hypothetical protein | - |
| EPB57_RS08880 | 147810..147887 | + | 78 | WP_154205184.1 | hypothetical protein | - |
| EPB57_RS23810 | 148117..148296 | + | 180 | WP_054866202.1 | hypothetical protein | - |
| EPB57_RS08890 | 148536..148814 | - | 279 | WP_005398411.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
| EPB57_RS08895 | 148811..149095 | - | 285 | WP_005398409.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| EPB57_RS23865 | 149172..149255 | + | 84 | Protein_129 | DUF3265 domain-containing protein | - |
| EPB57_RS08900 | 149292..149819 | + | 528 | WP_206666877.1 | CbrC family protein | - |
| EPB57_RS23815 | 149840..149932 | + | 93 | WP_193222928.1 | DUF3265 domain-containing protein | - |
| EPB57_RS08910 | 150387..150479 | + | 93 | WP_096030926.1 | DUF3265 domain-containing protein | - |
| EPB57_RS08915 | 150535..151116 | + | 582 | WP_154204501.1 | hypothetical protein | - |
| EPB57_RS23820 | 151134..151223 | + | 90 | WP_195723118.1 | DUF3265 domain-containing protein | - |
| EPB57_RS08925 | 151250..151696 | + | 447 | WP_101944980.1 | GNAT family N-acetyltransferase | - |
| EPB57_RS08935 | 152229..152366 | + | 138 | WP_081007947.1 | DUF3265 domain-containing protein | - |
| EPB57_RS08940 | 153237..153329 | + | 93 | WP_078235968.1 | DUF3265 domain-containing protein | - |
| EPB57_RS08945 | 153404..153787 | + | 384 | WP_193294301.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | vxsC / exsA / exsD / vscB / vscC / vscD / vscF / vscG / vscH / vscI / vscJ / vscK / vscL / vopS / vopR / vecA / vopQ / vscU / vscT / vscS / vscR / vscQ / vscO / vscN / vopN / tyeA/vcr1 / sycN/vcr2 / vscX / vscY / vcrD / vcrR / vcrG / vcrV / vcrH / vopB / vopD | 11598..303750 | 292152 | |
| - | inside | Integron | - | - | 148395..179951 | 31556 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10891.57 Da Isoelectric Point: 4.3430
>T118288 WP_005398411.1 NZ_CP035700:c148814-148536 [Vibrio alginolyticus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD
Download Length: 279 bp
>T118288 NZ_CP035700:c148814-148536 [Vibrio alginolyticus]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGTGTACAACGAGATGGCA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTATCTTACTGGGTTGAGGGCGATATCATCCGAGTTATG
CGTGTACTACACCAGAAACAAAAATTCCCTACGGATTGA
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGTGTACAACGAGATGGCA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTATCTTACTGGGTTGAGGGCGATATCATCCGAGTTATG
CGTGTACTACACCAGAAACAAAAATTCCCTACGGATTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 11069.40 Da Isoelectric Point: 9.2167
>AT118288 WP_005398409.1 NZ_CP035700:c149095-148811 [Vibrio alginolyticus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
Download Length: 285 bp
>AT118288 NZ_CP035700:c149095-148811 [Vibrio alginolyticus]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGAAC
TCTAAGTGATGCTTGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCTGTTTTCGTTGAGCACCAAACTGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGAAC
TCTAAGTGATGCTTGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCTGTTTTCGTTGAGCACCAAACTGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A347UR22 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A347UR21 |