Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE-RelB |
Location | 388206..388765 | Replicon | chromosome |
Accession | NZ_CP035698 | ||
Organism | Vibrio cincinnatiensis strain 2409-02 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A0F2I776 |
Locus tag | ET948_RS14645 | Protein ID | WP_045569735.1 |
Coordinates | 388487..388765 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | ET948_RS14640 | Protein ID | WP_154116224.1 |
Coordinates | 388206..388490 (+) | Length | 95 a.a. |
Genomic Context
Location: 383848..384675 (828 bp)
Type: Others
Protein ID: WP_154116220.1
Type: Others
Protein ID: WP_154116220.1
Location: 388206..388490 (285 bp)
Type: Antitoxin
Protein ID: WP_154116224.1
Type: Antitoxin
Protein ID: WP_154116224.1
Location: 388487..388765 (279 bp)
Type: Toxin
Protein ID: WP_045569735.1
Type: Toxin
Protein ID: WP_045569735.1
Location: 393171..393443 (273 bp)
Type: Others
Protein ID: WP_004394087.1
Type: Others
Protein ID: WP_004394087.1
Location: 384751..385332 (582 bp)
Type: Others
Protein ID: WP_154116222.1
Type: Others
Protein ID: WP_154116222.1
Location: 385370..386422 (1053 bp)
Type: Others
Protein ID: WP_195707330.1
Type: Others
Protein ID: WP_195707330.1
Location: 386793..386909 (117 bp)
Type: Others
Protein ID: Protein_319
Type: Others
Protein ID: Protein_319
Location: 386919..387221 (303 bp)
Type: Others
Protein ID: WP_000229324.1
Type: Others
Protein ID: WP_000229324.1
Location: 387209..387466 (258 bp)
Type: Others
Protein ID: WP_000861987.1
Type: Others
Protein ID: WP_000861987.1
Location: 388040..388150 (111 bp)
Type: Others
Protein ID: Protein_322
Type: Others
Protein ID: Protein_322
Location: 388914..389543 (630 bp)
Type: Others
Protein ID: WP_154116226.1
Type: Others
Protein ID: WP_154116226.1
Location: 389572..389685 (114 bp)
Type: Others
Protein ID: Protein_326
Type: Others
Protein ID: Protein_326
Location: 389686..390150 (465 bp)
Type: Others
Protein ID: WP_154116228.1
Type: Others
Protein ID: WP_154116228.1
Location: 390304..390918 (615 bp)
Type: Others
Protein ID: WP_154116229.1
Type: Others
Protein ID: WP_154116229.1
Location: 391005..391856 (852 bp)
Type: Others
Protein ID: WP_158147655.1
Type: Others
Protein ID: WP_158147655.1
Location: 391940..392161 (222 bp)
Type: Others
Protein ID: Protein_330
Type: Others
Protein ID: Protein_330
Location: 392321..392935 (615 bp)
Type: Others
Protein ID: WP_154116231.1
Type: Others
Protein ID: WP_154116231.1
Location: 392970..393131 (162 bp)
Type: Others
Protein ID: WP_154116881.1
Type: Others
Protein ID: WP_154116881.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ET948_RS14605 | 383848..384675 | + | 828 | WP_154116220.1 | sulfurtransferase | - |
ET948_RS14610 | 384751..385332 | - | 582 | WP_154116222.1 | DUF1287 domain-containing protein | - |
ET948_RS14615 | 385370..386422 | - | 1053 | WP_195707330.1 | ISAs1 family transposase | - |
ET948_RS14620 | 386793..386909 | - | 117 | Protein_319 | DUF3265 domain-containing protein | - |
ET948_RS14625 | 386919..387221 | - | 303 | WP_000229324.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
ET948_RS14630 | 387209..387466 | - | 258 | WP_000861987.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
ET948_RS14635 | 388040..388150 | - | 111 | Protein_322 | DUF3265 domain-containing protein | - |
ET948_RS14640 | 388206..388490 | + | 285 | WP_154116224.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
ET948_RS14645 | 388487..388765 | + | 279 | WP_045569735.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
ET948_RS14650 | 388914..389543 | - | 630 | WP_154116226.1 | FMN-binding negative transcriptional regulator | - |
ET948_RS14655 | 389572..389685 | - | 114 | Protein_326 | DUF3265 domain-containing protein | - |
ET948_RS14660 | 389686..390150 | - | 465 | WP_154116228.1 | ASCH domain-containing protein | - |
ET948_RS14665 | 390304..390918 | - | 615 | WP_154116229.1 | outer membrane beta-barrel protein | - |
ET948_RS14670 | 391005..391856 | - | 852 | WP_158147655.1 | IS3 family transposase | - |
ET948_RS14675 | 391940..392161 | - | 222 | Protein_330 | transposase | - |
ET948_RS14680 | 392321..392935 | - | 615 | WP_154116231.1 | hypothetical protein | - |
ET948_RS14685 | 392970..393131 | - | 162 | WP_154116881.1 | DUF3265 domain-containing protein | - |
ET948_RS14690 | 393171..393443 | + | 273 | WP_004394087.1 | DUF1778 domain-containing protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 384751..459423 | 74672 | |
- | inside | Integron | - | - | 387209..409983 | 22774 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10898.61 Da Isoelectric Point: 4.6794
>T118279 WP_045569735.1 NZ_CP035698:388487-388765 [Vibrio cincinnatiensis]
MIFWEEASLNDREKIFEFLYDFNPTAAEKTDELIETKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVDGSKIRIM
RVLHQKQKFPND
MIFWEEASLNDREKIFEFLYDFNPTAAEKTDELIETKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVDGSKIRIM
RVLHQKQKFPND
Download Length: 279 bp
>T118279 NZ_CP035698:388487-388765 [Vibrio cincinnatiensis]
ATGATTTTCTGGGAAGAAGCATCTCTCAATGATCGAGAGAAAATTTTCGAATTTCTTTACGACTTTAACCCAACCGCAGC
TGAAAAAACGGATGAGCTCATAGAAACAAAAGTTGAAAATTTGCTTGAGCAACCACTAATGGGTGTTCAGCGTGATGGTA
TTAGAGGCAGATTGCTTATTATCCCTGAGATATCAATGATTGTTTCGTATTGGGTTGATGGTTCTAAAATTCGAATAATG
CGTGTACTACATCAGAAACAAAAATTTCCAAACGACTGA
ATGATTTTCTGGGAAGAAGCATCTCTCAATGATCGAGAGAAAATTTTCGAATTTCTTTACGACTTTAACCCAACCGCAGC
TGAAAAAACGGATGAGCTCATAGAAACAAAAGTTGAAAATTTGCTTGAGCAACCACTAATGGGTGTTCAGCGTGATGGTA
TTAGAGGCAGATTGCTTATTATCCCTGAGATATCAATGATTGTTTCGTATTGGGTTGATGGTTCTAAAATTCGAATAATG
CGTGTACTACATCAGAAACAAAAATTTCCAAACGACTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10917.25 Da Isoelectric Point: 8.0775
>AT118279 WP_154116224.1 NZ_CP035698:388206-388490 [Vibrio cincinnatiensis]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKALSHDAWLTEQVNQAFEKFDSGKAVFIEHDIAKAR
MAERKAKIRNRGHS
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKALSHDAWLTEQVNQAFEKFDSGKAVFIEHDIAKAR
MAERKAKIRNRGHS
Download Length: 285 bp
>AT118279 NZ_CP035698:388206-388490 [Vibrio cincinnatiensis]
ATGGATACTAGAATTCAATTTCGTGTAGACGAAGAAACAAAACGTTTAGCTCAACAAATGGCTGAAAGCCAAGGTCGAAC
TCTTAGCGATGCTTGCCGTGAACTCACTGAACAATTAGCTGAGCAGCAACGCAAGGCATTATCTCACGATGCATGGTTAA
CTGAACAAGTGAATCAAGCATTTGAGAAGTTCGACTCAGGAAAAGCAGTATTCATTGAACATGACATCGCCAAAGCACGA
ATGGCTGAACGTAAAGCTAAAATCCGAAATCGAGGCCACTCATGA
ATGGATACTAGAATTCAATTTCGTGTAGACGAAGAAACAAAACGTTTAGCTCAACAAATGGCTGAAAGCCAAGGTCGAAC
TCTTAGCGATGCTTGCCGTGAACTCACTGAACAATTAGCTGAGCAGCAACGCAAGGCATTATCTCACGATGCATGGTTAA
CTGAACAAGTGAATCAAGCATTTGAGAAGTTCGACTCAGGAAAAGCAGTATTCATTGAACATGACATCGCCAAAGCACGA
ATGGCTGAACGTAAAGCTAAAATCCGAAATCGAGGCCACTCATGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0F2I776 |
Antitoxin
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Source | ID | Structure |
---|---|---|
No matching records found |