Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 388206..388765 Replicon chromosome
Accession NZ_CP035698
Organism Vibrio cincinnatiensis strain 2409-02

Toxin (Protein)


Gene name relE Uniprot ID A0A0F2I776
Locus tag ET948_RS14645 Protein ID WP_045569735.1
Coordinates 388487..388765 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ET948_RS14640 Protein ID WP_154116224.1
Coordinates 388206..388490 (+) Length 95 a.a.

Genomic Context


ET948_RS14605ET948_RS14640ET948_RS14645ET948_RS14690ET948_RS14610ET948_RS14615ET948_RS14620ET948_RS14625ET948_RS14630ET948_RS14635ET948_RS14650ET948_RS14655ET948_RS14660ET948_RS14665ET948_RS14670ET948_RS14675ET948_RS14680ET948_RS14685
Location: 383848..384675 (828 bp)
Type: Others
Protein ID: WP_154116220.1
Location: 388206..388490 (285 bp)
Type: Antitoxin
Protein ID: WP_154116224.1
Location: 388487..388765 (279 bp)
Type: Toxin
Protein ID: WP_045569735.1
Location: 393171..393443 (273 bp)
Type: Others
Protein ID: WP_004394087.1
Location: 384751..385332 (582 bp)
Type: Others
Protein ID: WP_154116222.1
Location: 385370..386422 (1053 bp)
Type: Others
Protein ID: WP_195707330.1
Location: 386793..386909 (117 bp)
Type: Others
Protein ID: Protein_319
Location: 386919..387221 (303 bp)
Type: Others
Protein ID: WP_000229324.1
Location: 387209..387466 (258 bp)
Type: Others
Protein ID: WP_000861987.1
Location: 388040..388150 (111 bp)
Type: Others
Protein ID: Protein_322
Location: 388914..389543 (630 bp)
Type: Others
Protein ID: WP_154116226.1
Location: 389572..389685 (114 bp)
Type: Others
Protein ID: Protein_326
Location: 389686..390150 (465 bp)
Type: Others
Protein ID: WP_154116228.1
Location: 390304..390918 (615 bp)
Type: Others
Protein ID: WP_154116229.1
Location: 391005..391856 (852 bp)
Type: Others
Protein ID: WP_158147655.1
Location: 391940..392161 (222 bp)
Type: Others
Protein ID: Protein_330
Location: 392321..392935 (615 bp)
Type: Others
Protein ID: WP_154116231.1
Location: 392970..393131 (162 bp)
Type: Others
Protein ID: WP_154116881.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
ET948_RS14605383848..384675+828WP_154116220.1sulfurtransferase-
ET948_RS14610384751..385332-582WP_154116222.1DUF1287 domain-containing protein-
ET948_RS14615385370..386422-1053WP_195707330.1ISAs1 family transposase-
ET948_RS14620386793..386909-117Protein_319DUF3265 domain-containing protein-
ET948_RS14625386919..387221-303WP_000229324.1type II toxin-antitoxin system RelE/ParE family toxin-
ET948_RS14630387209..387466-258WP_000861987.1type II toxin-antitoxin system Phd/YefM family antitoxin-
ET948_RS14635388040..388150-111Protein_322DUF3265 domain-containing protein-
ET948_RS14640388206..388490+285WP_154116224.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
ET948_RS14645388487..388765+279WP_045569735.1type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE familyToxin
ET948_RS14650388914..389543-630WP_154116226.1FMN-binding negative transcriptional regulator-
ET948_RS14655389572..389685-114Protein_326DUF3265 domain-containing protein-
ET948_RS14660389686..390150-465WP_154116228.1ASCH domain-containing protein-
ET948_RS14665390304..390918-615WP_154116229.1outer membrane beta-barrel protein-
ET948_RS14670391005..391856-852WP_158147655.1IS3 family transposase-
ET948_RS14675391940..392161-222Protein_330transposase-
ET948_RS14680392321..392935-615WP_154116231.1hypothetical protein-
ET948_RS14685392970..393131-162WP_154116881.1DUF3265 domain-containing protein-
ET948_RS14690393171..393443+273WP_004394087.1DUF1778 domain-containing protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--384751..45942374672
-insideIntegron--387209..40998322774


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 93 a.a.        Molecular weight: 10898.61 Da        Isoelectric Point: 4.6794

>T118279 WP_045569735.1 NZ_CP035698:388487-388765 [Vibrio cincinnatiensis]
MIFWEEASLNDREKIFEFLYDFNPTAAEKTDELIETKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVDGSKIRIM
RVLHQKQKFPND

Download         Length: 279 bp

>T118279 NZ_CP035698:388487-388765 [Vibrio cincinnatiensis]
ATGATTTTCTGGGAAGAAGCATCTCTCAATGATCGAGAGAAAATTTTCGAATTTCTTTACGACTTTAACCCAACCGCAGC
TGAAAAAACGGATGAGCTCATAGAAACAAAAGTTGAAAATTTGCTTGAGCAACCACTAATGGGTGTTCAGCGTGATGGTA
TTAGAGGCAGATTGCTTATTATCCCTGAGATATCAATGATTGTTTCGTATTGGGTTGATGGTTCTAAAATTCGAATAATG
CGTGTACTACATCAGAAACAAAAATTTCCAAACGACTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10917.25 Da        Isoelectric Point: 8.0775

>AT118279 WP_154116224.1 NZ_CP035698:388206-388490 [Vibrio cincinnatiensis]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKALSHDAWLTEQVNQAFEKFDSGKAVFIEHDIAKAR
MAERKAKIRNRGHS

Download         Length: 285 bp

>AT118279 NZ_CP035698:388206-388490 [Vibrio cincinnatiensis]
ATGGATACTAGAATTCAATTTCGTGTAGACGAAGAAACAAAACGTTTAGCTCAACAAATGGCTGAAAGCCAAGGTCGAAC
TCTTAGCGATGCTTGCCGTGAACTCACTGAACAATTAGCTGAGCAGCAACGCAAGGCATTATCTCACGATGCATGGTTAA
CTGAACAAGTGAATCAAGCATTTGAGAAGTTCGACTCAGGAAAAGCAGTATTCATTGAACATGACATCGCCAAAGCACGA
ATGGCTGAACGTAAAGCTAAAATCCGAAATCGAGGCCACTCATGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A0F2I776


Antitoxin

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Source
ID
Structure
No matching records found

References