Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/Phd(antitoxin) |
| Location | 2691767..2692314 | Replicon | chromosome |
| Accession | NZ_CP035693 | ||
| Organism | Vibrio harveyi strain 2011V-1164 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | EPB58_RS23030 | Protein ID | WP_130199208.1 |
| Coordinates | 2692012..2692314 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | U3A269 |
| Locus tag | EPB58_RS23025 | Protein ID | WP_005448240.1 |
| Coordinates | 2691767..2692024 (+) | Length | 86 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EPB58_RS22975 | 2687364..2688107 | + | 744 | WP_154203597.1 | hypothetical protein | - |
| EPB58_RS22980 | 2688202..2688696 | + | 495 | WP_154203598.1 | hypothetical protein | - |
| EPB58_RS22985 | 2688855..2689382 | + | 528 | WP_130193141.1 | hypothetical protein | - |
| EPB58_RS22990 | 2689409..2689501 | + | 93 | WP_193222943.1 | DUF3265 domain-containing protein | - |
| EPB58_RS22995 | 2689530..2689748 | + | 219 | Protein_2413 | hypothetical protein | - |
| EPB58_RS26695 | 2689773..2689864 | + | 92 | Protein_2414 | DUF3265 domain-containing protein | - |
| EPB58_RS23000 | 2689927..2690439 | + | 513 | WP_053306500.1 | hypothetical protein | - |
| EPB58_RS23005 | 2690452..2690592 | - | 141 | WP_154203600.1 | hypothetical protein | - |
| EPB58_RS23010 | 2690699..2690875 | + | 177 | WP_154203601.1 | hypothetical protein | - |
| EPB58_RS23015 | 2690879..2691283 | + | 405 | WP_069510005.1 | type II toxin-antitoxin system YafO family toxin | - |
| EPB58_RS23020 | 2691292..2691564 | + | 273 | WP_005445731.1 | hypothetical protein | - |
| EPB58_RS23025 | 2691767..2692024 | + | 258 | WP_005448240.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| EPB58_RS23030 | 2692012..2692314 | + | 303 | WP_130199208.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| EPB58_RS23035 | 2692441..2692917 | + | 477 | WP_154203602.1 | hypothetical protein | - |
| EPB58_RS23040 | 2693065..2693514 | + | 450 | WP_053343012.1 | GNAT family N-acetyltransferase | - |
| EPB58_RS23045 | 2693511..2693633 | + | 123 | WP_081469165.1 | DUF3265 domain-containing protein | - |
| EPB58_RS23050 | 2693690..2694274 | + | 585 | WP_154203603.1 | hypothetical protein | - |
| EPB58_RS26700 | 2694318..2694410 | + | 93 | WP_195724112.1 | DUF3265 domain-containing protein | - |
| EPB58_RS23060 | 2694439..2695239 | + | 801 | WP_154203604.1 | HNH endonuclease | - |
| EPB58_RS23065 | 2695497..2695931 | + | 435 | WP_154203605.1 | hypothetical protein | - |
| EPB58_RS23070 | 2695910..2696344 | + | 435 | WP_154203606.1 | hypothetical protein | - |
| EPB58_RS26705 | 2696344..2696448 | + | 105 | Protein_2430 | DUF3265 domain-containing protein | - |
| EPB58_RS23075 | 2696437..2696844 | + | 408 | WP_195724153.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2626626..2701535 | 74909 | |
| - | inside | Integron | - | - | 2625357..2695931 | 70574 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11683.60 Da Isoelectric Point: 5.1765
>T118277 WP_130199208.1 NZ_CP035693:2692012-2692314 [Vibrio harveyi]
MVEVIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLSKQ
MVEVIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLSKQ
Download Length: 303 bp
>T118277 NZ_CP035693:2692012-2692314 [Vibrio harveyi]
ATGGTTGAAGTAATCTGGACAGAACCAGCGTTATCTGACCTCAATGATATCGCTGAATACATAGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTGCAAACGATCTTCTCCAAAGTCGAACGCCTACAAACTTTCCCAGAATCAGGTCGTATTCCAC
CTGAACTAGAACATTTAAGTTATCGTGAAGTAGTCGTTAATCCATGTCGTGTCTTCTACAAACAAGACGGTGACAAAGTG
TTTATTCTTTTTGTTATGCGTGCAGAAAGAGATTTACGTAAGTTCTTGTTGAGTAAGCAATAA
ATGGTTGAAGTAATCTGGACAGAACCAGCGTTATCTGACCTCAATGATATCGCTGAATACATAGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTGCAAACGATCTTCTCCAAAGTCGAACGCCTACAAACTTTCCCAGAATCAGGTCGTATTCCAC
CTGAACTAGAACATTTAAGTTATCGTGAAGTAGTCGTTAATCCATGTCGTGTCTTCTACAAACAAGACGGTGACAAAGTG
TTTATTCTTTTTGTTATGCGTGCAGAAAGAGATTTACGTAAGTTCTTGTTGAGTAAGCAATAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9606.10 Da Isoelectric Point: 6.7269
>AT118277 WP_005448240.1 NZ_CP035693:2691767-2692024 [Vibrio harveyi]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKDKM
SKWLK
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKDKM
SKWLK
Download Length: 258 bp
>AT118277 NZ_CP035693:2691767-2692024 [Vibrio harveyi]
ATGAAAGTAGAACTAGTTACATCACTTAAACGTCAAGCAACTAAGATCCTCGCCGATCTCCACGATACCAAAGAACCAGT
GCTAATTACTGAGCATGGTAAGCCATCTGCGTATCTAGTTGATGTTGATGACTACGAATTTATGCAAAACCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCACTAGCTGACGGTAAAGTGGTAAGTCATGATGAAGCCAAGGACAAAATG
TCAAAATGGTTGAAGTAA
ATGAAAGTAGAACTAGTTACATCACTTAAACGTCAAGCAACTAAGATCCTCGCCGATCTCCACGATACCAAAGAACCAGT
GCTAATTACTGAGCATGGTAAGCCATCTGCGTATCTAGTTGATGTTGATGACTACGAATTTATGCAAAACCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCACTAGCTGACGGTAAAGTGGTAAGTCATGATGAAGCCAAGGACAAAATG
TCAAAATGGTTGAAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|