Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2276549..2276693 Replicon chromosome
Accession NZ_CP035633
Organism Enterobacter cloacae strain EN3600

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2276555..2276658 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2276549..2276693 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EVV94_RS11245 2271706..2273154 + 1449 WP_205742266.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EVV94_RS11250 2273261..2273500 + 240 WP_008500472.1 YebV family protein -
EVV94_RS11255 2273535..2274179 - 645 WP_094935589.1 protein-serine/threonine phosphatase -
EVV94_RS11260 2274346..2275287 + 942 WP_094935590.1 VirK/YbjX family protein -
EVV94_RS11265 2275461..2276357 + 897 WP_094935591.1 benzoate transporter -
- 2276549..2276693 + 145 - - Antitoxin
- 2276555..2276658 - 104 - - Toxin
EVV94_RS11270 2276797..2277135 - 339 WP_033145840.1 YebY family protein -
EVV94_RS11275 2277152..2278021 - 870 WP_094935592.1 copper homeostasis membrane protein CopD -
EVV94_RS11280 2278023..2278394 - 372 WP_094935593.1 CopC domain-containing protein YobA -
EVV94_RS11285 2278531..2278761 + 231 WP_013096102.1 DNA polymerase III subunit theta -
EVV94_RS11290 2278872..2279522 + 651 WP_033145843.1 carbon-nitrogen hydrolase family protein -
EVV94_RS11295 2279547..2280209 + 663 WP_010432611.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T118160 NZ_CP035633:c2276658-2276555 [Enterobacter cloacae]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT118160 NZ_CP035633:2276549-2276693 [Enterobacter cloacae]
ACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References