Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2301018..2301546 Replicon chromosome
Accession NZ_CP035632
Organism Synechococcus sp. RSCCF101

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag EVJ50_RS11235 Protein ID WP_150884041.1
Coordinates 2301018..2301281 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag EVJ50_RS11240 Protein ID WP_150884042.1
Coordinates 2301268..2301546 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EVJ50_RS11195 2296128..2296403 + 276 WP_150884033.1 DUF2282 domain-containing protein -
EVJ50_RS11200 2296445..2297269 + 825 WP_150884034.1 DUF692 domain-containing protein -
EVJ50_RS11205 2297266..2298078 + 813 WP_150884035.1 DNA-binding domain-containing protein -
EVJ50_RS11210 2298506..2298817 + 312 WP_150884036.1 hypothetical protein -
EVJ50_RS11215 2298920..2299378 + 459 WP_150884037.1 DUF1311 domain-containing protein -
EVJ50_RS11220 2299680..2299997 + 318 WP_150884038.1 hypothetical protein -
EVJ50_RS11225 2300092..2300418 + 327 WP_150884039.1 hypothetical protein -
EVJ50_RS11230 2300533..2300919 + 387 WP_191964754.1 hypothetical protein -
EVJ50_RS11235 2301018..2301281 + 264 WP_150884041.1 BrnT family toxin Toxin
EVJ50_RS11240 2301268..2301546 + 279 WP_150884042.1 CopG family transcriptional regulator Antitoxin
EVJ50_RS11245 2301695..2302951 + 1257 WP_150884043.1 ester cyclase -
EVJ50_RS11250 2302878..2303816 - 939 WP_150884044.1 AraC family transcriptional regulator -
EVJ50_RS11265 2304463..2306199 - 1737 WP_150884047.1 alpha-keto acid decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10069.50 Da        Isoelectric Point: 7.2778

>T118156 WP_150884041.1 NZ_CP035632:2301018-2301281 [Synechococcus sp. RSCCF101]
MNFECDPLKSAANQVKHGIDFLDAQALWSDPAVLEIPARTTDEPRFLVIGQIHRRHWSAVITYRGQAIRLISVRRSRPEE
VQLYEQL

Download         Length: 264 bp

>T118156 NZ_CP035632:2301018-2301281 [Synechococcus sp. RSCCF101]
ATGAACTTTGAGTGCGACCCGCTCAAGAGTGCGGCCAACCAGGTCAAGCACGGCATCGATTTCCTCGATGCGCAAGCCCT
CTGGAGTGATCCCGCCGTGCTCGAGATTCCAGCCCGTACCACCGATGAGCCACGGTTCCTCGTGATTGGCCAGATCCACC
GCAGGCACTGGTCGGCTGTGATCACGTATCGCGGCCAGGCCATCCGTCTCATTTCCGTCCGCCGCTCCCGCCCGGAAGAG
GTCCAGCTTTATGAACAGCTCTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10474.71 Da        Isoelectric Point: 5.7288

>AT118156 WP_150884042.1 NZ_CP035632:2301268-2301546 [Synechococcus sp. RSCCF101]
MNSSEFDRRVDDGESVVEALDLDGARRSRLQQKRVNVDFPLWMVERLDHEATRLGVTRQSIIKVWLAERLEHGRPAASSQ
ADSCLPSPQEKS

Download         Length: 279 bp

>AT118156 NZ_CP035632:2301268-2301546 [Synechococcus sp. RSCCF101]
ATGAACAGCTCTGAATTTGATCGGCGCGTTGATGACGGTGAGTCCGTGGTCGAGGCGCTCGATCTCGACGGTGCCCGTCG
ATCCCGCTTGCAACAGAAGCGCGTGAACGTGGATTTCCCCCTCTGGATGGTGGAGCGACTCGACCATGAGGCCACCCGGC
TCGGTGTGACCCGCCAGTCGATCATCAAGGTCTGGCTCGCAGAGCGTCTGGAGCACGGTCGGCCTGCCGCGTCGTCTCAA
GCCGACAGCTGCCTCCCTTCGCCGCAGGAGAAGAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References