Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1882522..1882666 | Replicon | chromosome |
| Accession | NZ_CP035540 | ||
| Organism | Klebsiella pneumoniae subsp. pneumoniae strain CCRI-22199 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1882558..1882660 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1882522..1882666 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| Kp711_RS11395 | 1877652..1879712 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| Kp711_RS11400 | 1879716..1880375 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| Kp711_RS11405 | 1880454..1880684 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| Kp711_RS11410 | 1880797..1881171 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| Kp711_RS11415 | 1881175..1882044 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| Kp711_RS11420 | 1882061..1882399 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1882522..1882666 | - | 145 | - | - | Antitoxin |
| - | 1882558..1882660 | + | 103 | - | - | Toxin |
| Kp711_RS11425 | 1882793..1883152 | - | 360 | WP_077253379.1 | tyrosine-type recombinase/integrase | - |
| Kp711_RS11430 | 1883151..1883630 | + | 480 | WP_032419797.1 | lysis protein | - |
| Kp711_RS11440 | 1884419..1885924 | + | 1506 | WP_020956680.1 | hypothetical protein | - |
| Kp711_RS11445 | 1886174..1886602 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| Kp711_RS11450 | 1886612..1886893 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1877685..1900637 | 22952 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T118094 NZ_CP035540:1882558-1882660 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT118094 NZ_CP035540:c1882666-1882522 [Klebsiella pneumoniae subsp. pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
