Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 2051228..2051736 Replicon chromosome
Accession NZ_CP035534
Organism Sulfurimonas sp. NW10

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag ETP70_RS10770 Protein ID WP_151901181.1
Coordinates 2051228..2051488 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ETP70_RS10775 Protein ID WP_151901182.1
Coordinates 2051491..2051736 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ETP70_RS10755 2047923..2050274 + 2352 WP_151901178.1 HD domain-containing protein -
ETP70_RS10760 2050411..2050773 + 363 WP_151901179.1 nucleotidyltransferase domain-containing protein -
ETP70_RS10765 2050763..2051167 + 405 WP_151901180.1 DUF86 domain-containing protein -
ETP70_RS10770 2051228..2051488 - 261 WP_151901181.1 Txe/YoeB family addiction module toxin Toxin
ETP70_RS10775 2051491..2051736 - 246 WP_151901182.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ETP70_RS10780 2051913..2052242 + 330 WP_151901183.1 type II toxin-antitoxin system RelE/ParE family toxin -
ETP70_RS10785 2052244..2052528 + 285 WP_151901184.1 XRE family transcriptional regulator -
ETP70_RS10790 2053025..2053225 - 201 WP_151901185.1 hypothetical protein -
ETP70_RS10795 2053449..2053700 - 252 WP_151901186.1 hypothetical protein -
ETP70_RS10800 2054293..2054604 + 312 WP_151901187.1 type II toxin-antitoxin system RelE/ParE family toxin -
ETP70_RS10805 2054612..2054908 + 297 WP_151901188.1 HigA family addiction module antidote protein -
ETP70_RS10810 2055083..2056189 - 1107 WP_151901189.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10336.83 Da        Isoelectric Point: 9.5799

>T118087 WP_151901181.1 NZ_CP035534:c2051488-2051228 [Sulfurimonas sp. NW10]
MLIGFADKGWEDYQYWVQNDKKVLKRINTLLEDIKRNPDDSNGLGKPERLKENYQGYFSRRITSEHRLVYKIINGLIVIA
QCRYHY

Download         Length: 261 bp

>T118087 NZ_CP035534:c2051488-2051228 [Sulfurimonas sp. NW10]
ATGCTTATAGGGTTTGCTGATAAAGGCTGGGAAGATTATCAGTATTGGGTACAAAATGATAAAAAAGTATTAAAAAGAAT
CAATACACTTCTTGAAGATATCAAGAGAAATCCTGATGATTCAAACGGGCTTGGAAAACCCGAGAGACTGAAGGAAAATT
ATCAAGGCTATTTTTCAAGAAGAATCACATCTGAACATAGACTGGTTTATAAAATCATCAATGGACTTATTGTAATAGCA
CAGTGCAGGTATCACTACTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9450.63 Da        Isoelectric Point: 4.7571

>AT118087 WP_151901182.1 NZ_CP035534:c2051736-2051491 [Sulfurimonas sp. NW10]
MQAVFYSQARNNLRSIIDKVCDDFDEYIITTKNNKSAVIMSYDEYSSLKETLYLLGSKNNRDRLNDAIEQIESSKFITKE
I

Download         Length: 246 bp

>AT118087 NZ_CP035534:c2051736-2051491 [Sulfurimonas sp. NW10]
ATGCAAGCTGTATTTTATTCACAAGCAAGAAATAATCTCAGAAGTATCATAGATAAAGTCTGTGATGACTTCGATGAGTA
CATAATTACTACAAAAAACAACAAGTCTGCTGTCATCATGTCTTATGATGAATATAGTTCCCTGAAAGAAACTCTGTATC
TATTGGGTTCAAAAAACAATAGAGATAGACTAAACGATGCTATTGAGCAGATTGAAAGCAGTAAATTCATTACAAAAGAG
ATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References