Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1138024..1138537 Replicon chromosome
Accession NZ_CP035534
Organism Sulfurimonas sp. NW10

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag ETP70_RS05980 Protein ID WP_151900326.1
Coordinates 1138024..1138296 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag ETP70_RS05985 Protein ID WP_151901515.1
Coordinates 1138286..1138537 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ETP70_RS05940 1133492..1133716 + 225 WP_151900318.1 hypothetical protein -
ETP70_RS05945 1133887..1135059 + 1173 WP_151900319.1 hypothetical protein -
ETP70_RS05950 1135213..1136184 + 972 WP_151900320.1 hypothetical protein -
ETP70_RS05955 1136252..1136497 + 246 WP_151900321.1 hypothetical protein -
ETP70_RS05960 1136614..1136802 + 189 WP_151900322.1 hypothetical protein -
ETP70_RS05965 1136787..1137107 + 321 WP_151900323.1 type II toxin-antitoxin system RelE/ParE family toxin -
ETP70_RS05970 1137213..1137512 + 300 WP_151900324.1 type II toxin-antitoxin system HigB family toxin -
ETP70_RS05975 1137514..1137885 + 372 WP_151900325.1 DNA-binding protein -
ETP70_RS05980 1138024..1138296 + 273 WP_151900326.1 BrnT family toxin Toxin
ETP70_RS05985 1138286..1138537 + 252 WP_151901515.1 CopG family transcriptional regulator Antitoxin
ETP70_RS05990 1138677..1139225 + 549 WP_151899460.1 ISAs1 family transposase -
ETP70_RS05995 1139300..1139782 + 483 WP_151901516.1 ISAs1 family transposase -
ETP70_RS06000 1139872..1140144 + 273 WP_151900327.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
ETP70_RS06005 1140141..1140473 + 333 WP_151900328.1 type II toxin-antitoxin system RelE/ParE family toxin -
ETP70_RS06015 1140652..1140897 + 246 WP_151900329.1 Rho-binding antiterminator -
ETP70_RS06020 1140967..1141410 + 444 WP_151900330.1 hypothetical protein -
ETP70_RS06025 1141687..1142007 + 321 WP_151900331.1 hypothetical protein -
ETP70_RS06030 1142040..1142441 - 402 WP_151900332.1 hemerythrin family protein -
ETP70_RS06035 1142460..1142747 - 288 WP_151900333.1 NifU family protein -
ETP70_RS06040 1142806..1143210 - 405 WP_151900334.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - flgG 1122500..1480444 357944
- inside Integron - - 1124159..1139225 15066


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-81)

Antitoxin

CopG antitoxin

(8-71)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10680.13 Da        Isoelectric Point: 5.8803

>T118086 WP_151900326.1 NZ_CP035534:1138024-1138296 [Sulfurimonas sp. NW10]
VKFEYDDTKSQINKEKHGIDFVEAQKLWQDEDALVVPANIVDNEIRYALISKILTKCFVVIFTIREDTNRIISVRRCRKN
EEKNYENNNC

Download         Length: 273 bp

>T118086 NZ_CP035534:1138024-1138296 [Sulfurimonas sp. NW10]
GTGAAATTTGAGTATGATGATACGAAAAGTCAAATCAATAAAGAGAAACATGGCATAGATTTTGTAGAAGCTCAAAAGCT
TTGGCAAGATGAGGATGCACTTGTTGTTCCTGCTAACATTGTTGATAATGAAATTCGCTATGCACTCATCTCAAAAATAC
TCACAAAATGTTTTGTTGTAATATTTACTATAAGAGAAGACACAAATAGAATTATTAGTGTTCGAAGATGTAGGAAAAAT
GAGGAGAAGAATTATGAAAACAATAACTGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9652.88 Da        Isoelectric Point: 5.1750

>AT118086 WP_151901515.1 NZ_CP035534:1138286-1138537 [Sulfurimonas sp. NW10]
ITAKEFDEKFDNGEDISEYLDFSQATRPNALKTDTKKVNVDFPQWVIDSLDKEAKKIGVTRQSIIKVWIAERLKEETRHL
QVS

Download         Length: 252 bp

>AT118086 NZ_CP035534:1138286-1138537 [Sulfurimonas sp. NW10]
ATAACTGCTAAAGAGTTTGATGAGAAGTTTGATAATGGTGAAGACATAAGTGAATATCTTGATTTTTCACAAGCTACCAG
ACCTAATGCTCTTAAAACAGATACAAAAAAAGTTAATGTAGATTTCCCACAATGGGTTATAGACTCTTTAGACAAAGAAG
CAAAAAAGATAGGTGTAACTAGACAGTCTATCATTAAAGTTTGGATTGCTGAAAGGCTTAAAGAAGAAACTAGGCACTTA
CAAGTAAGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References